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高密度脂蛋白对饮酒和戒酒的反应作为酒精性肝病患者肝功能的一个指标

High-density lipoprotein response to alcohol consumption and abstinence as an indicator of liver function in alcoholic patients.

作者信息

Devenyi P, Kapur B M, Roy J H

出版信息

Can Med Assoc J. 1984 Jun 1;130(11):1445-7.

PMID:6733615
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1483334/
Abstract

A study of 36 alcoholic men admitted to hospital when intoxicated was undertaken to confirm the value of changes in the level of high-density lipoprotein cholesterol (HDL) as an indicator of liver function in patients with chronic alcoholism. In the patients without severe liver disease the HDL level was high after the recent consumption of alcohol and usually dropped by 0.2 mmol/L or more after 1 or 2 weeks of abstinence. In contrast, in the patients with severe alcoholic liver disease the HDL level was initially low and generally remained low after abstinence.

摘要

一项针对36名醉酒后入院的男性酗酒者的研究开展了,以证实高密度脂蛋白胆固醇(HDL)水平变化作为慢性酒精中毒患者肝功能指标的价值。在没有严重肝病的患者中,近期饮酒后HDL水平较高,而在戒酒1或2周后通常会下降0.2 mmol/L或更多。相比之下,在患有严重酒精性肝病的患者中,HDL水平最初较低,戒酒之后总体仍保持较低水平。

相似文献

1
High-density lipoprotein response to alcohol consumption and abstinence as an indicator of liver function in alcoholic patients.高密度脂蛋白对饮酒和戒酒的反应作为酒精性肝病患者肝功能的一个指标
Can Med Assoc J. 1984 Jun 1;130(11):1445-7.
2
Alcohol and high-density lipoproteins.酒精与高密度脂蛋白
Can Med Assoc J. 1980 Nov 22;123(10):981-4.
3
The relationship between alcohol consumption, liver enzymes and high-density lipoprotein cholesterol.
Circulation. 1981 Sep;64(3 Pt 2):III 67-72.
4
High-density lipoproteins from human alcoholics exhibit impaired reverse cholesterol transport function.来自人类酗酒者的高密度脂蛋白表现出逆向胆固醇转运功能受损。
Metabolism. 2000 Nov;49(11):1406-10. doi: 10.1053/meta.2000.17728.
5
[Serum lipoproteins in chronic alcoholics. Changes in HDL, VLDL and LDL as a function of the degree of hepatic involvement].
Nouv Presse Med. 1982 Oct 30;11(43):3179-83.
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High-density lipoprotein cholesterol in male alcoholics with and without severe liver disease.患有和未患有严重肝病的男性酗酒者的高密度脂蛋白胆固醇
Am J Med. 1981 Oct;71(4):589-94. doi: 10.1016/0002-9343(81)90211-4.
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[Serum lipoprotein fractions in chronic liver diseases with and without alcoholism].[伴有或不伴有酒精中毒的慢性肝病中的血清脂蛋白组分]
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8
[Concentration of lipids and apolipoproteins A-I, A-II and E in blood plasma of men with chronic alcoholism].[慢性酒精中毒男性血浆中脂质及载脂蛋白A-I、A-II和E的浓度]
Vopr Med Khim. 1981 May-Jun;27(3):397-402.
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Alcohol and high-density lipoprotein cholesterol.
Circulation. 1981 Sep;64(3 Pt 2):III 63-7.
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Platelet aggregation and plasma lipoproteins in alcoholics during alcohol withdrawal.酒精戒断期间酗酒者的血小板聚集和血浆脂蛋白
Thromb Haemost. 1986 Apr 30;55(2):173-7.

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Liver disease in the alcoholic.酗酒者的肝脏疾病
Can Fam Physician. 1986 Sep;32:1938-89.
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Chronic alcohol exposure negatively impacts the physiological and molecular parameters of the renal biotin reabsorption process.慢性酒精暴露会对肾脏生物素重吸收过程的生理和分子参数产生负面影响。
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本文引用的文献

1
High-density lipoprotein cholesterol in male alcoholics with and without severe liver disease.患有和未患有严重肝病的男性酗酒者的高密度脂蛋白胆固醇
Am J Med. 1981 Oct;71(4):589-94. doi: 10.1016/0002-9343(81)90211-4.
2
Alcohol and high-density lipoproteins.酒精与高密度脂蛋白
Can Med Assoc J. 1980 Nov 22;123(10):981-4.
3
High-density lipoprotein cholesterol and liver disease.高密度脂蛋白胆固醇与肝脏疾病
Hepatology. 1983 May-Jun;3(3):343-8. doi: 10.1002/hep.1840030311.
4
Assessment of prognostic factors in alcoholic liver disease: toward a global quantitative expression of severity.酒精性肝病预后因素评估:迈向严重程度的全球定量表达。
Hepatology. 1983 Nov-Dec;3(6):896-905. doi: 10.1002/hep.1840030602.
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Increase in plasma alpha-lipoproteins in chronic alcoholics after acute abuse.
Acta Med Scand. 1974 Apr;195(4):273-7. doi: 10.1111/j.0954-6820.1974.tb08137.x.
6
Coffee, alcohol and risk of coronary heart disease among Japanese men living in Hawaii.夏威夷日本男性中咖啡、酒精与冠心病风险
N Engl J Med. 1977 Aug 25;297(8):405-9. doi: 10.1056/NEJM197708252970801.
7
Effect of short-term therapy with propylthiouracil in patients with alcoholic liver disease.丙硫氧嘧啶短期治疗对酒精性肝病患者的影响。
Gastroenterology. 1979 Jan;76(1):105-15.
8
Alcoholic liver disease: the problem of diagnosis.酒精性肝病:诊断问题
Alcohol Clin Exp Res. 1978 Oct;2(4):327-38. doi: 10.1111/j.1530-0277.1978.tb04738.x.
9
Plasma lipids and lipoproteins in liver disease.肝病中的血浆脂质与脂蛋白
Gut. 1978 Jun;19(6):526-30. doi: 10.1136/gut.19.6.526.
10
Multi-laboratory comparison of three heparin-Mn2+ precipitation procedures for estimating cholesterol in high-density lipoprotein.三种用于估算高密度脂蛋白中胆固醇的肝素-Mn2+沉淀法的多实验室比较
Clin Chem. 1978 Jun;24(6):853-6.