Vernersson E
Acta Anaesthesiol Scand. 1984 Jun;28(3):325-30. doi: 10.1111/j.1399-6576.1984.tb02070.x.
Anesthetized piglets were subjected to a standardized full thickness skin burn, covering one third of the body surface area, and given fluid treatment. One group was also submitted to early excision of the burned area 5 h after the burn and another group was excised and given lysine-vasopressin by continuous infusion. In both the excised groups there was earlier circulatory restitution compared with the conservatively treated animals. After 24 h, cardiac function was best in the pigs treated with vasopressin and excision. The mechanisms by which vasopressin treatment and excision might have favourable circulatory effects in burn treatment are discussed.
将麻醉后的仔猪进行标准化的全层皮肤烧伤，烧伤面积覆盖身体表面积的三分之一，并给予液体治疗。一组在烧伤后5小时还接受了烧伤区域的早期切除，另一组进行了切除并通过持续输注给予赖氨酸加压素。与保守治疗的动物相比，两个切除组的循环恢复都更早。24小时后，接受加压素治疗和切除的猪的心脏功能最佳。文中讨论了加压素治疗和切除在烧伤治疗中可能产生有利循环影响的机制。
