Harvey P D, Earle-Boyer E A, Wielgus M S
J Nerv Ment Dis. 1984 Aug;172(8):458-63. doi: 10.1097/00005053-198408000-00003.
This report presents an assessment of 20 manic and 20 schizophrenic patients using a clinical rating instrument: the Scale for Assessment of Thought, Language, and Communication (TLC). These 40 patients were assessed three times within a 10-day period at the outset of an acute psychotic episode with open-ended interviews which were then evaluated with the TLC. It was found that clinically rated speech disorders were relatively consistent within these patients at the outset of a psychotic episode. Furthermore, it was found that composite ratings of positive and negative speech disorders, as defined by the TLC, were stable discriminators of the manic and schizophrenic patients, while global thought disorder was not useful as a discriminator. The results provide evidence that thought disorder in psychosis may be a stable trait of patients during acute episodes and that positive and negative disorder is a useful construct.
思维、语言和沟通评定量表（TLC），对20名躁狂症患者和20名精神分裂症患者进行了评估。这40名患者在急性精神病发作开始后的10天内接受了三次评估，采用开放式访谈，随后用TLC进行评估。结果发现，在精神病发作开始时，这些患者的临床评定言语障碍相对一致。此外，研究发现，TLC所定义的阳性和阴性言语障碍综合评定，是躁狂症和精神分裂症患者的稳定鉴别指标，而整体思维障碍作为鉴别指标并无用处。研究结果表明，精神病中的思维障碍可能是患者急性发作期间的一种稳定特征，且阳性和阴性障碍是一种有用的概念。
