Taylor M A, Reed R, Berenbaum S
Department of Psychiatry, Finch University of Health Sciences, Chicago Medical School, Illinois 60064.
J Nerv Ment Dis. 1994 Jun;182(6):319-26. doi: 10.1097/00005053-199406000-00002.
Formal thought disorder (FTD), defined as abnormal speech, has been associated with schizophrenia and likened to fluent aphasia. Whether FTD differentiates subtypes of schizophrenics and discriminates schizophrenics from other patients is unclear. We studied this issue by analyzing ratings of FTD of 170 schizophrenics and 62 manics. Eighty percent of emotionally blunted schizophrenics had FTD compared with 6.5% of manics. Factor analysis revealed verbiage disturbance and disorganized speech factors (44% of the variance). We assessed the discriminating ability of these factors, and compared these results to those from factors derived from Andreasen's positive/negative FTD construct, and to factors derived from speech and language diagnostic criteria for schizophrenia and mania in the proposed DSM-IV. Overall classifications were similar (91%, 91%, and 88%, respectively). We also found that FTD was related to emotional blunting, but not to other psychopathology.
形式思维障碍（FTD）被定义为言语异常，与精神分裂症相关，并被比作流畅性失语。FTD是否能区分精神分裂症的亚型以及将精神分裂症患者与其他患者区分开来尚不清楚。我们通过分析170名精神分裂症患者和62名躁狂症患者的FTD评分来研究这个问题。情感迟钝的精神分裂症患者中有80%存在FTD，而躁狂症患者中这一比例为6.5%。因子分析揭示了言语紊乱和言语不连贯因素（占方差的44%）。我们评估了这些因素的鉴别能力，并将这些结果与源自安德烈亚森的阳性/阴性FTD结构的因素以及源自拟议的《精神疾病诊断与统计手册》第四版中精神分裂症和躁狂症的言语和语言诊断标准的因素进行了比较。总体分类相似（分别为91%、91%和88%）。我们还发现FTD与情感迟钝有关，但与其他精神病理学无关。
