葡萄糖对酿酒酵母中转化酶合成的调控
Regulation of invertase synthesis by glucose in Saccharomyces cerevisiae.
作者信息
Mormeneo S, Sentandreu R
出版信息
J Bacteriol. 1982 Oct;152(1):14-8. doi: 10.1128/jb.152.1.14-18.1982.
Abstract
Saccharomyces cerevisiae growing under repressible conditions (1% of glucose or more) produces a burst of external invertase when shifted to higher temperatures. The secretion of this invertase requires protein synthesis, but was found to be independent of RNA formation. The level of mRNA accumulated and translated was inversely proportional to the glucose present in the growth medium. These results are consistent with the hypothesis that invertase is continuously synthesized both in the presence and absence of glucose, but under repressible conditions is degraded before secretion takes place.
摘要
在可阻遏条件下（葡萄糖含量为1%或更高）生长的酿酒酵母，当转移到较高温度时会产生一阵胞外转化酶。这种转化酶的分泌需要蛋白质合成，但发现其与RNA形成无关。积累并翻译的mRNA水平与生长培养基中存在的葡萄糖呈反比。这些结果与以下假设一致：无论有无葡萄糖，转化酶都在持续合成，但在可阻遏条件下，在分泌发生之前就被降解了。
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本文引用的文献
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