Dussourd d'Hinterland L, Pinel A M, Rey G
Arzneimittelforschung. 1980;30(1a):132-41.
Ribosomal vaccines prepared from purified bacterial ribosomes induce the production of specific antibodies in female OF1 mice when administered to the animals both with incomplete Freund's adjuvant or purified Klebsiella pneumoniae cell wall proteoglycans. The study of these fractions concerned purified ribosomes extracted from the following bacteria: Klebsiella pneumoniae, Haemophilius influenzae, Steptococcus pneumoniae, Streptococcus pyogenes A12. Specific antibodies determination by immunoelectro diffusion (IED) and passive hemagglutination (PHA) were used to study the immune response.
用纯化的细菌核糖体制备的核糖体疫苗,当与不完全弗氏佐剂或纯化的肺炎克雷伯菌细胞壁蛋白聚糖一起给雌性OF1小鼠接种时,可诱导其产生特异性抗体。对这些组分的研究涉及从以下细菌中提取的纯化核糖体:肺炎克雷伯菌、流感嗜血杆菌、肺炎链球菌、化脓性链球菌A12。通过免疫电扩散(IED)和被动血凝反应(PHA)测定特异性抗体,以研究免疫反应。