Pavlova I G, Medvedev D I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(7):1058-68.
Electron microscopy was used to study the effect of durative protein-caloric insufficiency on the ultrastructure of neurons in the V brain layer of 40-day mice. The perikaryon of most nervous cells showed insignificant elements of destruction, focal rarification of ribosomes, deaggregation of Nissl's substance, expansion of the cysterns in the cytoplasmic network, changes in mitochondria, etc. In the cytoplasm of separate neurons, the destructive processes were more pronounced and involved almost the whole cytoplasm. They were also found in most dendrites of large and medium size of the V cortical layer. At the same time most neurons demonstrated marked signs of the compensatory-adaptive processes (an increase in the amount of folds in the nuclear membrane, an increase in the quantity of lisosomes, an enhanced activity of the axo-dendric part of the synapses, etc.).
采用电子显微镜研究持续性蛋白质-热量不足对40日龄小鼠大脑V层神经元超微结构的影响。大多数神经细胞的胞体显示出轻微的破坏迹象，核糖体局部稀疏，尼氏体解聚，细胞质网络中的池扩张，线粒体变化等。在个别神经元的细胞质中，破坏过程更为明显，几乎涉及整个细胞质。在V皮质层大多数大中型树突中也发现了这些变化。与此同时，大多数神经元表现出明显的代偿-适应过程迹象（核膜褶皱数量增加、溶酶体数量增加、突触轴突-树突部分活性增强等）。
