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[促甲状腺激素释放激素(TRH)前后循环甲状腺激素、T3摄取及促甲状腺激素的正常值。对182名甲状腺功能正常儿童的放射免疫分析测定(作者译)]

[Normal values for circulating thyroid hormones, T3 uptake and thyrotropin before and after TRH. Radioimmunoassay determinations on 182 euthyroid children (author's transl)].

作者信息

Borkenstein M, Stöffler G, Stögmann W, Fueger G, Falk W

出版信息

Monatsschr Kinderheilkd (1902). 1980 Jun;128(6):422-7.

PMID:6775189
Abstract

Measurements of T4, T3, rT3, T3U, and TSH (before and after TRH stimulation) were performed by RIA. 182 children, apparently euthyroid, age 2/12--14 years, were investigated in a cross sectional study. Free T4RIA and free T3RIA Indices and the ratio rT3/T3 and T4/T3 were calculated. Statistical analysis showed the following results: 1. Geometric mean serum concentrations of T4, T3, rT3 and TSH (basal) show no age related differences; T4 showed a not significant negative slope with age.--2. The ratio rT3/T3 and T4/T3 remains constant.--3. TRH induced TSH release (indicating the activity of the regulatory system) is unchanged from 2/12 to 14 years. Geometric means values, standard deviations and normal ranges are given.

摘要

采用放射免疫分析法(RIA)测定T4、T3、反T3(rT3)、T3摄取试验(T3U)以及促甲状腺激素(TSH)(促甲状腺激素释放激素(TRH)刺激前后)。在一项横断面研究中,对182名年龄在2/12至14岁、甲状腺功能明显正常的儿童进行了调查。计算游离T4放射免疫分析和游离T3放射免疫分析指标以及rT3/T3和T4/T3比值。统计分析结果如下:1. T4、T3、rT3和TSH(基础值)的几何平均血清浓度无年龄相关差异;T4随年龄增长呈不显著的负斜率。——2. rT3/T3和T4/T3比值保持恒定。——3. 从2/12岁至14岁,TRH诱导的TSH释放(表明调节系统的活性)未发生变化。给出了几何平均值、标准差和正常范围。

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