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在低胸苷含量的穆勒-欣顿琼脂上检测到的胸苷依赖性肠球菌的发生率。

Incidence of thymidine-dependent enterococci detected on Mueller-Hinton agar with low thymidine content.

作者信息

Haltiner R C, Migneault P C, Robertson R G

出版信息

Antimicrob Agents Chemother. 1980 Sep;18(3):365-8. doi: 10.1128/AAC.18.3.365.

DOI:10.1128/AAC.18.3.365
PMID:6775593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC284006/
Abstract

It was observed that 10% of urine culture isolates of enterococci tested for antimicrobial susceptibility failed to grow on commercially prepared Mueller-Hinton agar with low levels of thymidine and thymine. All strains could utilize exogenous thymidine and thymine and required only low levels (0.4-microgram disk) to support growth. All thymidine-thymine-requiring strains were resistant to trimethoprim-sulfamethoxazole.

摘要

据观察，在接受抗菌药敏试验的肠球菌尿液培养分离物中，有10%在含有低水平胸苷和胸腺嘧啶的商业制备的穆勒-欣顿琼脂上无法生长。所有菌株都能利用外源性胸苷和胸腺嘧啶，且仅需低水平（0.4微克纸片）即可支持生长。所有需要胸苷-胸腺嘧啶的菌株对甲氧苄啶-磺胺甲恶唑耐药。

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Incidence of thymidine-dependent enterococci detected on Mueller-Hinton agar with low thymidine content.在低胸苷含量的穆勒-欣顿琼脂上检测到的胸苷依赖性肠球菌的发生率。
Antimicrob Agents Chemother. 1980 Sep;18(3):365-8. doi: 10.1128/AAC.18.3.365.
2
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J Clin Microbiol. 1984 Jan;19(1):85-6. doi: 10.1128/jcm.19.1.85-86.1984.
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Co-trimoxazole (trimethoprim-sulfamethoxazole): an updated review of its antibacterial activity and clinical efficacy.复方新诺明（甲氧苄啶-磺胺甲恶唑）：抗菌活性及临床疗效的最新综述
Drugs. 1982 Dec;24(6):459-518. doi: 10.2165/00003495-198224060-00002.
4
Infection caused by thymidine-requiring, trimethoprim-resistant bacteria.由需要胸苷、对甲氧苄啶耐药的细菌引起的感染。
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5
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J Clin Microbiol. 1987 Oct;25(10):1886-90. doi: 10.1128/jcm.25.10.1886-1890.1987.

本文引用的文献

1
Letter: Is co-trimoxazole bactericidal in sputum?信件：复方新诺明在痰液中具有杀菌作用吗？
Br Med J. 1973 Oct 20;4(5885):165. doi: 10.1136/bmj.4.5885.165-b.
2
Use of trimethoprim to obtain thymine-requiring mutants of Streptococcus faecalis.使用甲氧苄啶获得粪肠球菌的胸腺嘧啶需求型突变体。
J Gen Microbiol. 1973 Jan;74(1):195-9. doi: 10.1099/00221287-74-1-195.
3
Thymine dependent strains of Escherichia coli selected by trimethoprim-sulphamethoxazole therapy.
Pathology. 1974 Apr;6(2):161-7. doi: 10.3109/00313027409068980.
4
Thymine-requiring mutants of Proteus mirabilis selected by co-trimoxazole in vivo.
J Gen Microbiol. 1973 Aug;77(2):533-5. doi: 10.1099/00221287-77-2-533.
5
Characteristics of some co-trimoxazole-resistant Enterobacteriaceae from infected patients.感染患者中部分耐复方新诺明肠杆菌科细菌的特征。
J Clin Pathol. 1972 Dec;25(12):1086-8. doi: 10.1136/jcp.25.12.1086.
6
Recognition of group D streptococcal species of human origin by biochemical and physiological tests.通过生化和生理学测试识别源自人类的D组链球菌菌种。
Appl Microbiol. 1972 Jun;23(6):1131-9. doi: 10.1128/am.23.6.1131-1139.1972.
7
Comparison of several laboratory media for presumptive identification of enterococci and group D streptococci.几种用于初步鉴定肠球菌和D群链球菌的实验室培养基的比较。
Appl Microbiol. 1973 Aug;26(2):138-45. doi: 10.1128/am.26.2.138-145.1973.
8
Human infections with thymine-requiring bacteria.人类感染需胸腺嘧啶的细菌。
J Med Microbiol. 1978 Feb;11(1):33-45. doi: 10.1099/00222615-11-1-33.
9
Presumptive identification of group A, B, and D streptococci on agar plate media.在琼脂平板培养基上对A、B和D组链球菌进行初步鉴定。
J Clin Microbiol. 1979 Jun;9(6):665-72. doi: 10.1128/jcm.9.6.665-672.1979.
10
Letter: Thymine-requiring bacteria.信件：需胸腺嘧啶的细菌。
Lancet. 1976 May 15;1(7968):1080.