多组分疫苗和福尔马林灭活细胞疫苗对水貂铜绿假单胞菌所致地方性出血性肺炎的保护效果比较。
Comparison of the effects of a multi-component vaccine and a formalin-killed cell vaccine on protection against enzootic of hemorrhagic pneumonia due to Pseudomonas aeruginosa in mink.
作者信息
Abe C, Homma J Y, Noda H, Yanagawa R, Morihara K, Tsuzuki H, Takeuchi S
出版信息
Zentralbl Bakteriol A. 1981 Aug;249(3):413-7.
Effectiveness of a multi-component vaccine consisting of the common antigen (OEP) derived from Pseudomonas aeruginosa strain N 10 (serotype E) and toxoids of protease and elastase was compared with that of formalin-killed cells of strain N 10 on protection against enzootic of hemorrhagic pneumonia due to P. aeruginosa in mink. One administration of the multi-component vaccine (100 microgram each of OEP, protease toxoid and elastase toxoid) clearly prevented enzootic of hemorrhagic pneumonia due to P. aeruginosa (serotype G) in mink, while a vaccination of formalin-killed cells was much less effective in preventing an epidemic. The difference in mortality rates between two vaccines was remarkable.
将源自铜绿假单胞菌N 10菌株（血清型E）的共同抗原（OEP）以及蛋白酶和弹性蛋白酶类毒素组成的多组分疫苗，与N 10菌株的福尔马林灭活细胞在保护水貂抵抗由铜绿假单胞菌引起的出血性肺炎地方病方面的效果进行了比较。一次接种多组分疫苗（OEP、蛋白酶类毒素和弹性蛋白酶类毒素各100微克）能明显预防水貂因铜绿假单胞菌（血清型G）引起的出血性肺炎地方病，而接种福尔马林灭活细胞在预防疫情方面效果要差得多。两种疫苗的死亡率差异显著。
Zotero 插件