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相似文献

1
Heat-shock proteins of Drosophila are associated with nuclease-resistant, high-salt-resistant nuclear structures.果蝇的热休克蛋白与耐核酸酶、耐高盐的核结构相关。
J Cell Biol. 1981 Sep;90(3):793-6. doi: 10.1083/jcb.90.3.793.
2
Small heat shock proteins of Drosophila associate with the cytoskeleton.果蝇的小分子热休克蛋白与细胞骨架相关联。
Proc Natl Acad Sci U S A. 1986 Jan;83(1):90-4. doi: 10.1073/pnas.83.1.90.
3
The structure of nucleosomal core particles within transcribed and repressed gene regions.转录和抑制基因区域内核小体核心颗粒的结构。
Nucleic Acids Res. 1988 Dec 9;16(23):11187-205. doi: 10.1093/nar/16.23.11187.
4
Fractionation of nucleosomes by salt elution from micrococcal nuclease-digested nuclei.通过从微球菌核酸酶消化的细胞核中进行盐洗脱来分离核小体。
J Cell Biol. 1978 Oct;79(1):97-109. doi: 10.1083/jcb.79.1.97.
5
[Properties of mouse spleen residual condensed chromatin associated with the nuclear matrix].[与核基质相关的小鼠脾脏残余浓缩染色质的性质]
Mol Biol (Mosk). 1983 Jul-Aug;17(4):840-5.
6
Occurrence of intranuclear aggregates on nuclease digestion of isolated rat ascites hepatoma nuclei.分离的大鼠腹水肝癌细胞核经核酸酶消化后出现核内聚集体。
Cell Mol Biol. 1983;29(6):539-47.
7
[The structure of nucleosomal core particles located on the transcribed genome regions].
Mol Biol (Mosk). 1988 May-Jun;22(3):706-17.
8
Nucleosome dissociation at physiological ionic strengths.生理离子强度下的核小体解离
Nucleic Acids Res. 1981 Jan 24;9(2):445-57. doi: 10.1093/nar/9.2.445.
9
The release of 40S hnRNP particles by brief digestion of HeLa nuclei with micrococcal nuclease.用微球菌核酸酶短暂消化HeLa细胞核后释放出40S核不均一核糖核蛋白颗粒。
Nucleic Acids Res. 1980 Aug 25;8(16):3639-57. doi: 10.1093/nar/8.16.3639.
10
Chicken erythrocyte nucleus contains two classes of chromatin that differ in micrococcal nuclease susceptibility and solubility at physiological ionic strength.鸡红细胞核含有两类染色质，它们在微球菌核酸酶敏感性和生理离子强度下的溶解度方面存在差异。
Proc Natl Acad Sci U S A. 1981 Oct;78(10):5968-72. doi: 10.1073/pnas.78.10.5968.

引用本文的文献

1
Biomolecular phase separation in stress granule assembly and virus infection.应激颗粒组装和病毒感染中的生物分子相分离。
Acta Biochim Biophys Sin (Shanghai). 2023 Jul 3;55(7):1099-1118. doi: 10.3724/abbs.2023117.
2
Acquisition of Thermotolerance in Soybean Seedlings : Synthesis and Accumulation of Heat Shock Proteins and their Cellular Localization.大豆幼苗耐热性的获得：热激蛋白的合成与积累及其细胞定位。
Plant Physiol. 1984 Jan;74(1):152-60. doi: 10.1104/pp.74.1.152.
3
Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts.中国仓鼠成纤维细胞中热休克蛋白合成与耐热性发展之间的相关性。
Proc Natl Acad Sci U S A. 1982 May;79(10):3218-22. doi: 10.1073/pnas.79.10.3218.
4
Modulation of protein synthesis in primary myogenic cells from chicken by cultivation in the serum-free, hormonally defined medium 'DMN'.通过在无血清、激素限定培养基“DMN”中培养来调节鸡原代成肌细胞中的蛋白质合成。
Experientia. 1983 Apr 15;39(4):347-50. doi: 10.1007/BF01963115.
5
Formation of cytoplasmic heat shock granules in tomato cell cultures and leaves.番茄细胞培养物和叶片中细胞质热激颗粒的形成。
Mol Cell Biol. 1983 Sep;3(9):1648-55. doi: 10.1128/mcb.3.9.1648-1655.1983.
6
"Prompt" heat shock proteins: translationally regulated synthesis of new proteins associated with the nuclear matrix-intermediate filaments as an early response to heat shock.“快速”热休克蛋白：新蛋白质的翻译调控合成与核基质中间丝相关，作为对热休克的早期反应。
Proc Natl Acad Sci U S A. 1983 Aug;80(15):4737-41. doi: 10.1073/pnas.80.15.4737.
7
Heat shock protein in mammalian brain and other organs after a physiologically relevant increase in body temperature induced by D-lysergic acid diethylamide.由麦角酸二乙酰胺诱导体温生理性升高后哺乳动物脑及其他器官中的热休克蛋白
Proc Natl Acad Sci U S A. 1983 Jan;80(2):569-73. doi: 10.1073/pnas.80.2.569.
8
A major heat-shock protein defined by a monoclonal antibody.一种由单克隆抗体定义的主要热休克蛋白。
EMBO J. 1984 Aug;3(8):1871-9. doi: 10.1002/j.1460-2075.1984.tb02061.x.
9
Quantitation and intracellular localization of the 85K heat shock protein by using monoclonal and polyclonal antibodies.利用单克隆抗体和多克隆抗体对85K热休克蛋白进行定量及细胞内定位研究。
Mol Cell Biol. 1984 Dec;4(12):2802-10. doi: 10.1128/mcb.4.12.2802-2810.1984.
10
Association between the mammalian 110,000-dalton heat-shock protein and nucleoli.哺乳动物110,000道尔顿热休克蛋白与核仁之间的关联。
J Cell Biol. 1983 Nov;97(5 Pt 1):1389-95. doi: 10.1083/jcb.97.5.1389.

本文引用的文献

1
Varying patterns of protein synthesis in Drosophila during heat shock: implications for regulation.果蝇在热休克期间蛋白质合成的不同模式：对调控的影响
Dev Biol. 1980 Jun 15;77(2):463-79. doi: 10.1016/0012-1606(80)90488-1.
2
A fixed site of DNA replication in eucaryotic cells.真核细胞中DNA复制的固定位点。
Cell. 1980 Feb;19(2):527-36. doi: 10.1016/0092-8674(80)90527-9.
3
The nuclear envelope lamina is reversibly depolymerized during mitosis.核膜层在有丝分裂期间可逆地解聚。
Cell. 1980 Jan;19(1):277-87. doi: 10.1016/0092-8674(80)90409-2.
4
Nucleosome structure.核小体结构。
Annu Rev Biochem. 1980;49:1115-56. doi: 10.1146/annurev.bi.49.070180.005343.
5
Translational control of protein synthesis in response to heat shock in D. melanogaster cells.黑腹果蝇细胞中蛋白质合成的翻译控制对热休克的响应。
Cell. 1980 Dec;22(3):825-34. doi: 10.1016/0092-8674(80)90559-0.
6
Heat shock, deciliation and release from anoxia induce the synthesis of the same set of polypeptides in starved T. pyriformis.
Cell. 1980 Nov;22(1 Pt 1):299-307. doi: 10.1016/0092-8674(80)90177-4.
7
Intracellular localization of heat shock proteins in Drosophila.果蝇中热休克蛋白的细胞内定位
Cell. 1980 Jul;20(3):679-89. doi: 10.1016/0092-8674(80)90314-1.
8
The 5' ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I.染色质中果蝇热休克基因的5'端对脱氧核糖核酸酶I高度敏感。
Nature. 1980 Aug 28;286(5776):854-60. doi: 10.1038/286854a0.
9
Translational efficiency of heat-induced messages in Drosophila melanogaster cells.黑腹果蝇细胞中热诱导信息的翻译效率。
J Mol Biol. 1980 Feb 25;137(2):151-8. doi: 10.1016/0022-2836(80)90322-8.
10
DNase I hypersensitive sites in Drosophila chromatin occur at the 5' ends of regions of transcription.果蝇染色质中的脱氧核糖核酸酶I超敏感位点出现在转录区域的5'端。
Proc Natl Acad Sci U S A. 1981 Jan;78(1):143-6. doi: 10.1073/pnas.78.1.143.

果蝇的热休克蛋白与耐核酸酶、耐高盐的核结构相关。

Heat-shock proteins of Drosophila are associated with nuclease-resistant, high-salt-resistant nuclear structures.

作者信息

Levinger L, Varshavsky A

出版信息

J Cell Biol. 1981 Sep;90(3):793-6. doi: 10.1083/jcb.90.3.793.

DOI:10.1083/jcb.90.3.793
PMID:6793602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2111893/
Abstract

Proteins produced in cultured Drosophila cells during the heat-shock response (HSPs) were recently shown by autoradiography to be confined in large measure to the cell nucleus. We report here that nuclear HSPs are not associated with nucleosomes solubilizes by treatment with staphylococcal nuclease at low ionic strength nor are HSPs released by extraction with high salt, which solubilized most of the remaining histones and DNA. Possible functions of nuclear HSPs are discussed.

摘要

最近通过放射自显影法显示，在热休克反应（HSPs）期间培养的果蝇细胞中产生的蛋白质在很大程度上局限于细胞核。我们在此报告，核HSPs与在低离子强度下用葡萄球菌核酸酶处理而溶解的核小体不相关，并且HSPs也不会因用高盐提取而释放，高盐提取可溶解大部分剩余的组蛋白和DNA。文中讨论了核HSPs可能的功能。