Leszczynski D E, Kummerow F A
Experientia. 1982 Feb 15;38(2):266-7. doi: 10.1007/BF01945105.
Lysine and arginine supplements were fed to 5-day-old chicks to test whether they would develop hypercholesterolemia in response to excess lysine in a fashion similar to mammals. Chicks developed hypercholesterolemia with a 4-5% lysine but not with arginine supplementation. These results indicate the lysine induced hypercholesterolemia is not due to anaplerotic interactions of arginine and lysine with the urea cycle.
给5日龄雏鸡喂食赖氨酸和精氨酸补充剂，以测试它们是否会像哺乳动物一样，因赖氨酸过量而出现高胆固醇血症。雏鸡在补充4-5%赖氨酸时出现了高胆固醇血症，但补充精氨酸时未出现。这些结果表明，赖氨酸诱导的高胆固醇血症并非由于精氨酸和赖氨酸与尿素循环的回补反应相互作用所致。
