Van Bruggen J T, Chalmers B, Muller M
J Gen Physiol. 1982 Mar;79(3):507-28. doi: 10.1085/jgp.79.3.507.
The present study compares and quantitates both solvent drag and solute drag forces in a system with both heteropore and homopore membranes. It is shown that tracer solute permeability can be increased if solution flow or driver solute flux is in the direction of tracer diffusion. Either force can decrease tracer permeability if the force can decrease tracer permeability if the force is opposite to the direction of tracer diffusion. The two forces can be additive or one force may reduce the effect of the other force. In the particular system quantitated, solute drag is shown to be some 300 times more effective than solvent drag on a mole-to-mole basis. The use of a number of solute pairs on other homopore and heteropore membranes confirms the finding that the two drag forces can be analyzed or manipulated in a variety of systems.
本研究比较并定量了具有异质孔和同质孔膜的系统中的溶剂拖曳力和溶质拖曳力。结果表明，如果溶液流动或驱动溶质通量与示踪剂扩散方向一致，示踪剂溶质渗透率会增加。如果力与示踪剂扩散方向相反，这两种力中的任何一种都可能降低示踪剂渗透率。这两种力可以是相加的，或者一种力可能会降低另一种力的作用。在所定量的特定系统中，按摩尔比计算，溶质拖曳力比溶剂拖曳力有效约300倍。在其他同质孔和异质孔膜上使用多种溶质对证实了这一发现，即在各种系统中都可以分析或控制这两种拖曳力。
