Brunnemann K D, Hoffmann D
IARC Sci Publ (1971). 1978(19):343-56.
Chemical-analytical data were presented illustrating that the mainstream smoke of tobacco products contains traces of volatile N-nitrosamines. The quantity of volatile nitrosamines in the sidestream smoke of cigarettes and cigars exceeds that in the mainstream smoke by at least a factor of 10. This observation led to model studies and analysis of air in bar cars of trains, in a local bar and other indoor atmospheres polluted by tobacco smoke. The results showed that, during one hour in a smoke-polluted indoor environment, one may inhale volatile nitrosamines in quantities equal to those in the mainstream smoke of 0.5-30 cigarettes. It is emphasized that there are, at present, no epidemiological data linking human respiratory cancers to volatile nitrosamines.
提供的化学分析数据表明,烟草制品的主流烟雾中含有痕量挥发性N-亚硝胺。香烟和雪茄侧流烟雾中的挥发性亚硝胺含量比主流烟雾中的至少高出10倍。这一观察结果促使人们对火车酒吧车厢、当地酒吧以及其他受烟草烟雾污染的室内环境中的空气进行模型研究和分析。结果显示,在烟雾污染的室内环境中呆上一小时,人吸入的挥发性亚硝胺量相当于0.5至30支香烟主流烟雾中的含量。需要强调的是,目前尚无将人类呼吸道癌症与挥发性亚硝胺联系起来的流行病学数据。