Linnet K
Gut. 1983 Mar;24(3):249-52. doi: 10.1136/gut.24.3.249.
Fasting and postprandial plasma concentrations of glycine and taurine conjugates of cholic, chenodeoxycholic, and deoxycholic acid were measured by a high pressure liquid chromatography-enzymatic assay in nine healthy subjects. The mean value of each bile acid concentration increased significantly (2.4-4.7 times) in the postprandial period. The total glycine taurine ratio of 2.5 in the fasting state increased significantly to a maximum value of 3.3 at one to 1 1/2 hours postprandially and then declined. This shift in glycine taurine ratio shows, that the relative increase in concentrations of glycine conjugates exceeds the relative increase in concentrations of taurine conjugates in the early postprandial period, and supports the view that there is significant absorption of glycine conjugated bile acids from the proximal small intestine.
通过高压液相色谱 - 酶法测定了9名健康受试者空腹和餐后胆酸、鹅去氧胆酸和脱氧胆酸的甘氨酸和牛磺酸共轭物的血浆浓度。每种胆汁酸浓度的平均值在餐后显著增加（2.4 - 4.7倍）。空腹状态下甘氨酸与牛磺酸的总比值为2.5，餐后1至1.5小时显著增加至最大值3.3，然后下降。甘氨酸与牛磺酸比值的这种变化表明，餐后早期甘氨酸共轭胆汁酸浓度的相对增加超过了牛磺酸共轭胆汁酸浓度的相对增加，这支持了近端小肠存在大量甘氨酸共轭胆汁酸吸收的观点。
