Dahl K B, Nyfors A, Brodthagen H
Arch Dermatol Res. 1978 Jun 29;262(1):131-4. doi: 10.1007/BF00455580.
In 56 patients leucocyte and differential counts were done before and at weekly intervals during PUVA treatment of chronic recalcitrant psoriasis. A statistical significant (P less than 0.01) decrease in the percentage of neutrophils was observed during the first week of the PUVA therapy. This observation could be closely related to the clinical clearing of psoriasis (P = 0.02). The effect of PUVA therapy in psoriasis may be due to a decrease in the number of immunocompetent neutrophils demonstrated in psoriatic lesions.
对56例慢性顽固性银屑病患者在进行补骨脂素长波紫外线（PUVA）治疗前及治疗期间每周进行白细胞及分类计数。在PUVA治疗的第一周观察到中性粒细胞百分比有统计学显著下降（P<0.01）。这一观察结果可能与银屑病的临床清除密切相关（P = 0.02）。PUVA治疗银屑病的效果可能是由于银屑病皮损中具有免疫活性的中性粒细胞数量减少所致。
