Green D, Maize J C
J Am Acad Dermatol. 1982 Sep;7(3):388-92. doi: 10.1016/s0190-9622(82)70125-2.
A 42-year-old black woman, gravida V, para IV, developed a recurrence of pemphigus vulgaris in the third trimester of pregnancy. She delivered a 2,056-gm stillborn female fetus in the seventh month, 2 days after ultrasonography had demonstrated absence of fetal cardiac activity and other evidence of intrauterine fetal death. The macerated fetus had peeling of its skin and an intact bulla on the foot. Fetal cardiac blood, obtained after delivery, showed the presence of pemphigus antibodies at a titer of 20. Direct immunofluorescence of fetal skin demonstrated IgG in the epidermal intercellular spaces. Autolytic changes of the skin, however, precluded definitive histologic documentation of acantholytic disease.
一名42岁的黑人女性,孕5产4,在妊娠晚期寻常型天疱疮复发。她在妊娠第七个月时分娩了一名体重2056克的死产女胎,超声检查显示胎儿心脏活动消失及其他宫内胎儿死亡迹象两天后分娩。浸软的胎儿皮肤有脱皮现象,足部有一个完整的水疱。分娩后获得的胎儿心脏血液显示天疱疮抗体滴度为20。胎儿皮肤的直接免疫荧光显示表皮细胞间间隙有IgG。然而,皮肤的自溶变化排除了棘层松解性疾病的确切组织学记录。