类风湿关节炎与骨关节炎患者血清1,25 - 二羟胆钙化醇浓度的比较。
Comparison of serum 1,25-dihydroxycholecalciferol concentrations in rheumatoid arthritis and osteoarthrosis.
作者信息
Bird H A, Wright V, Hennes U, Theiss E
出版信息
Ann Rheum Dis. 1982 Jun;41(3):257-8. doi: 10.1136/ard.41.3.257.
Abstract
We have previously compared 25-hydroxycholecalciferol levels in the serum of patients with osteoarthrosis and rheumatoid arthritis, finding no significant difference between the circulating levels of this hormone. We have now estimated 1,25-dihydroxycholecalciferol levels on stored sera from the same groups of patients and found no significant difference in the levels of this hormone between the 2 groups. The osteopenia that distinguishes rheumatoid arthritis from osteoarthrosis is not the result of altered levels of systemic 25OHD3 or of 1,25(OH)2D3. Local factors may be more important in its pathogenesis.
摘要
我们之前比较了骨关节炎和类风湿关节炎患者血清中的25-羟胆钙化醇水平，发现这种激素的循环水平之间没有显著差异。我们现在对同一组患者储存血清中的1,25-二羟胆钙化醇水平进行了评估，发现两组之间这种激素的水平没有显著差异。类风湿关节炎与骨关节炎相区别的骨质减少并非全身25OHD3或1,25(OH)2D3水平改变所致。局部因素在其发病机制中可能更为重要。
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