鸡卵清蛋白基因中12个内含子-外显子连接处的核苷酸序列同源性。
Nucleotide sequence homology at 12 intron--exon junctions in the chick ovalbumin gene.
作者信息
Catterall J F, O'Malley B W, Robertson M A, Staden R, Tanaka Y, Brownlee G G
出版信息
Nature. 1978 Oct 12;275(5680):510-3. doi: 10.1038/275510a0.
DOI:10.1038/275510a0
PMID:692731
Abstract
A short partial sequence homology is present at all intron-exon junctions, or splice points, in the chick ovalbumin gene; it is probably a signal for a splicing enzyme. The significance of the junction sequences for splicing is discussed. We find no evidence of strong Watson-Crick base pairing between adjacent junctions.
摘要
在鸡卵清蛋白基因的所有内含子-外显子连接处，即剪接位点，都存在一段短的部分序列同源性；它可能是一种剪接酶的信号。文中讨论了连接序列对于剪接的重要性。我们没有发现相邻连接处之间存在强沃森-克里克碱基配对的证据。
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