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自闭症儿童体内的甲状腺激素。

Thyroid hormone in autistic children.

作者信息

Cohen D J, Young J G, Lowe T L, Harcherik D

出版信息

J Autism Dev Disord. 1980 Dec;10(4):445-50. doi: 10.1007/BF02414820.

DOI:10.1007/BF02414820
PMID:6927746
Abstract

Thyroid hormone plays an important role in the pre- and postnatal development and function of the central nervous system. Disturbances in thyroid hormone regulation have been hypothesized in childhood autism. We evaluated blood indices of thyroid function, including serum thyroxine, triiodothyronine, and thyroid-stimulating hormone, in a large population of autistic children. No differences were found between autistic and normal children.

摘要

甲状腺激素在中枢神经系统的产前和产后发育及功能中起着重要作用。童年自闭症被推测与甲状腺激素调节紊乱有关。我们评估了大量自闭症儿童的甲状腺功能血液指标,包括血清甲状腺素、三碘甲状腺原氨酸和促甲状腺激素。自闭症儿童与正常儿童之间未发现差异。

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Thyroid hormone in autistic children.自闭症儿童体内的甲状腺激素。
J Autism Dev Disord. 1980 Dec;10(4):445-50. doi: 10.1007/BF02414820.
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Monatsschr Kinderheilkd (1902). 1980 Jun;128(6):422-7.

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本文引用的文献

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Treatment of psychoses in early childhood with trilodothyronine.用三碘甲状腺原氨酸治疗幼儿期精神病。
Am J Psychiatry. 1958 Aug;115(2):166-7. doi: 10.1176/ajp.115.2.166.
2
Catecholamine-thyroid hormone interactions: I. Thyroid hormone and platelet MAO activity in psychiatrically disturbed children.儿茶酚胺 - 甲状腺激素相互作用:I. 精神障碍儿童的甲状腺激素与血小板单胺氧化酶活性
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Catecholamine-thyroid hormone interactions: II. Thyroid hormone and platelet MAO activity in patients with thyroid disorders.
超越大脑:自闭症谱系障碍的多系统炎症亚型。
Psychopharmacology (Berl). 2019 Oct;236(10):3045-3061. doi: 10.1007/s00213-019-05280-6. Epub 2019 May 28.
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Biochemical assessments of thyroid profile, serum 25-hydroxycholecalciferol and cluster of differentiation 5 expression levels among children with autism.自闭症儿童甲状腺功能、血清25-羟基维生素D及分化簇5表达水平的生化评估。
Neuropsychiatr Dis Treat. 2017 Sep 14;13:2397-2403. doi: 10.2147/NDT.S146152. eCollection 2017.
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Prenatal and neonatal thyroid stimulating hormone levels and autism spectrum disorders.产前及新生儿促甲状腺激素水平与自闭症谱系障碍
J Autism Dev Disord. 2015 Mar;45(3):719-30. doi: 10.1007/s10803-014-2227-2.
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Newborn screening for autism: in search of candidate biomarkers.新生儿自闭症筛查:寻找候选生物标志物。
Biomark Med. 2013 Apr;7(2):247-60. doi: 10.2217/bmm.12.108.
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Investigation of the serum levels of anterior pituitary hormones in male children with autism.男性孤独症儿童血清垂体前叶激素水平的研究。
Mol Autism. 2011 Oct 19;2:16. doi: 10.1186/2040-2392-2-16.
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The screening and diagnosis of autistic spectrum disorders.自闭症谱系障碍的筛查与诊断
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9
Clinical neurochemistry of autism and associated disorders.自闭症及相关疾病的临床神经化学
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儿茶酚胺 - 甲状腺激素相互作用:II. 甲状腺疾病患者的甲状腺激素与血小板单胺氧化酶活性
Schizophr Bull. 1982;8(2):301-5. doi: 10.1093/schbul/8.2.301.
4
Serum triiodothyronine concentrations in infancy, childhood, adolescence and pediatric thyroid disorders.
J Clin Endocrinol Metab. 1973 Aug;37(2):235-7. doi: 10.1210/jcem-37-2-235.
5
Plasma catecholamines in hypothyroidism and hyperthyroidism.甲状腺功能减退和甲状腺功能亢进时的血浆儿茶酚胺
J Clin Endocrinol Metab. 1973 Mar;36(3):587-9. doi: 10.1210/jcem-36-3-587.
6
Plasma noradrenaline and adrenaline in patients with thyrotoxicosis and myxoedema.甲状腺毒症和黏液性水肿患者的血浆去甲肾上腺素和肾上腺素
Clin Sci Mol Med. 1973 Aug;45(2):163-71. doi: 10.1042/cs0450163.
7
Biogenic amines in autistic and atypical children. Cerebrospinal fluid measures of homovanillic acid and 5-hydroxyindoleacetic acid.自闭症及非典型儿童体内的生物胺。脑脊液中高香草酸和5-羟吲哚乙酸的检测指标
Arch Gen Psychiatry. 1974 Dec;31(6):845-53. doi: 10.1001/archpsyc.1974.01760180085011.
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Influence of pituitary, thyroid, and adrenal hormones on norepinephrine turnover and metabolism in the rat heart.垂体、甲状腺和肾上腺激素对大鼠心脏去甲肾上腺素周转及代谢的影响。
Circ Res. 1968 May;22(5):559-71. doi: 10.1161/01.res.22.5.559.
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Observations on the dopaminergic nature of hyperthyroid chorea.
J Neural Transm. 1972;33(1):73-81. doi: 10.1007/BF01244729.
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Radioimmunoassay of thyrotropin in human serum.人血清促甲状腺激素的放射免疫测定
J Clin Endocrinol Metab. 1965 Sep;25(9):1179-88. doi: 10.1210/jcem-25-9-1179.