Gelfman S S, Dionne R A, Driscoll E J
Anesth Prog. 1981 Sep-Oct;28(5):126-8.
The incidence of venous complications following intravenous diazepam administered to 190 dental out-patients was investigated in a prospective, randomized study. The administration into the smaller veins of the hand and forearm resulted in a significant increase in the incidence of thrombophlebitis. Use of a plastic catheter in place of an infusion needle or flushing with 150 ml of saline did not alter the incidence of venous complications. These results suggest that use of the larger veins of the antecubital fossa can lower the incidence of venous complications encountered in clinical practice following the intravenous administration of diazepam. These findings also suggest that use of a plastic catheter or post-drug administration flushing with saline does not affect the incidence of venous complications.
在一项前瞻性随机研究中，对190名牙科门诊患者静脉注射地西泮后的静脉并发症发生率进行了调查。在手和前臂的较小静脉中给药导致血栓性静脉炎的发生率显著增加。使用塑料导管代替输液针或用150毫升生理盐水冲洗并没有改变静脉并发症的发生率。这些结果表明，使用肘前窝的较大静脉可以降低临床实践中静脉注射地西泮后遇到的静脉并发症的发生率。这些发现还表明，使用塑料导管或给药后用生理盐水冲洗不会影响静脉并发症的发生率。
