T淋巴细胞产生中性粒细胞迁移抑制因子（NIF-T）过程中对B淋巴细胞同种抗原的需求。
Requirement for B-lymphocyte alloantigen in the production of neutrophil migration inhibition factor from T lymphocytes (NIF-T).
作者信息
Weisbart R H, Billing R
出版信息
Immunology. 1980 Apr;39(4):577-82.
Neutrophil migration inhibition factor from T lymphocytes (NIF-T) is produced in response to mitogens as the result of cellular interactions between T and B lymphocytes. The requirement for B-cell alloantigen in this interaction process was indicated by (1) collaboration between peripheral blood T cells with various B lymphoblast cell lines but not with non-B lymphoblast cells for NIF-T production, (2) inhibition of NIF-T production by treating collaborating B lymphoblasts with B-cell specific antiserum, and (3) inhibition of NIF-T production by peripheral blood lypmphocytes in the presence of anti-B-cell antiserum and F(ab')2 with anti-B-cell specificity.
T淋巴细胞产生的中性粒细胞迁移抑制因子（NIF-T）是在有丝分裂原刺激下，T淋巴细胞和B淋巴细胞之间细胞相互作用的结果。这种相互作用过程中对B细胞同种异体抗原的需求通过以下几点得以表明：（1）外周血T细胞与各种B淋巴母细胞系合作可产生NIF-T，而与非B淋巴母细胞则不能合作；（2）用B细胞特异性抗血清处理合作的B淋巴母细胞可抑制NIF-T的产生；（3）在存在抗B细胞抗血清和具有抗B细胞特异性的F(ab')2的情况下，外周血淋巴细胞可抑制NIF-T的产生。
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