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Mutations in nif genes that cause Klebsiella pneumoniae to be derepressed for nitrogenase synthesis in the presence of ammonium.在铵存在的情况下，导致肺炎克雷伯菌对固氮酶合成去阻遏的固氮基因中的突变。
J Bacteriol. 1980 Nov;144(2):744-51. doi: 10.1128/jb.144.2.744-751.1980.
2
Glutamine synthetase mutations which affect expression of nitrogen fixation genes in Klebsiella pneumoniae.影响肺炎克雷伯菌中固氮基因表达的谷氨酰胺合成酶突变。
J Bacteriol. 1979 Nov;140(2):597-606. doi: 10.1128/jb.140.2.597-606.1979.
3
Nitrogenase synthesis in Klebsiella pneumoniae: enhanced nif expression without accumulation of guanosine 5'-diphosphate 3'-diphosphate.肺炎克雷伯菌中固氮酶的合成：nif表达增强且无3′，5′-二磷酸鸟苷积累
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Regulation of nitrogenase synthesis in histidine auxotrophs of Klebsiella pneumoniae with altered levels of adenylate nucleotides.肺炎克雷伯菌组氨酸营养缺陷型中腺苷酸核苷酸水平改变对固氮酶合成的调控
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Control of Klebsiella pneumoniae nif mRNA synthesis.肺炎克雷伯菌固氮酶mRNA合成的调控
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A molecular genetic study of nif expression in Klebsiella pneumoniae at the level of transcription, translation and nitrogenase activity.肺炎克雷伯菌中固氮基因表达在转录、翻译和固氮酶活性水平的分子遗传学研究。
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Regulation of nitrogen fixation in Klebsiella pneumoniae: evidence for a role of glutamine synthetase as a regulator of nitrogenase synthesis.肺炎克雷伯菌中固氮作用的调控：谷氨酰胺合成酶作为固氮酶合成调节剂作用的证据。
J Bacteriol. 1974 Nov;120(2):815-21. doi: 10.1128/jb.120.2.815-821.1974.

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Control of nitrogen fixation in bacteria that associate with cereals.与谷物共生的细菌中固氮作用的控制。
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Construction of new yeast vectors and cloning of the nif (nitrogen fixation) gene cluster of Klebsiella pneumoniae in yeast.在酵母中构建新的酵母载体并克隆肺炎克雷伯氏菌的 nif（氮固定）基因簇。
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Nitrogen control of the nif regulon in Klebsiella pneumoniae: involvement of the ntrA gene and analogies between ntrC and nifA.肺炎克雷伯菌中固氮基因簇的氮调控：ntrA基因的作用以及ntrC与nifA之间的相似性
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5
Temperature sensitivity of the regulation of nitrogenase synthesis by Klebsiella pneumoniae.肺炎克雷伯菌对固氮酶合成调控的温度敏感性
J Bacteriol. 1981 Feb;145(2):1116-8. doi: 10.1128/jb.145.2.1116-1118.1981.
6
Regulation of nitrogen fixation in Klebsiella pneumoniae: isolation and characterization of strains with nif-lac fusions.肺炎克雷伯菌中固氮作用的调控：携带nif - lac融合基因菌株的分离与特性分析
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Overproduction of nitrogenase by nitrogen-limited cultures of Rhodopseudomonas palustris.沼泽红假单胞菌氮限制培养物中固氮酶的过量产生。
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8
Repression of nitrogen fixation in Klebsiella pneumoniae at high temperature.高温下肺炎克雷伯菌中固氮作用的抑制
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9
Nitrogen fixation by Klebsiella pneumoniae is inhibited by certain multicopy hybrid nif plasmids.肺炎克雷伯菌的固氮作用受到某些多拷贝杂种nif质粒的抑制。
J Bacteriol. 1983 Jan;153(1):45-56. doi: 10.1128/jb.153.1.45-56.1983.
10
Constitutive expression of nitrogen fixation (nif) genes of Klebsiella pneumoniae due to a DNA duplication.由于DNA重复导致肺炎克雷伯菌固氮（nif）基因的组成型表达。
EMBO J. 1982;1(12):1551-8. doi: 10.1002/j.1460-2075.1982.tb01354.x.

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The use of translocatable genetic elements to construct a fine-structure map of the Klebsiella pneumoniae nitrogen fixation (nif) gene cluster.利用可转位遗传元件构建肺炎克雷伯菌固氮（nif）基因簇的精细结构图。
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Regulation of nitrogen fixation in Klebsiella pneumoniae: evidence for a role of glutamine synthetase as a regulator of nitrogenase synthesis.肺炎克雷伯菌中固氮作用的调控：谷氨酰胺合成酶作为固氮酶合成调节剂作用的证据。
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在铵存在的情况下，导致肺炎克雷伯菌对固氮酶合成去阻遏的固氮基因中的突变。

Mutations in nif genes that cause Klebsiella pneumoniae to be derepressed for nitrogenase synthesis in the presence of ammonium.

作者信息

MacNeil D, Brill W J

出版信息

J Bacteriol. 1980 Nov;144(2):744-51. doi: 10.1128/jb.144.2.744-751.1980.

DOI:10.1128/jb.144.2.744-751.1980
PMID:7000753
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC294724/
Abstract

Four Nif+ revertants from strains with polar insertions in nifL, were insensitive to ammonium and amino acid repression of nitrogenase synthesis. These strains have mutations located in or near the nifL region. The derepressed phenotype was dominant in a merodiploid containing a nif+ plasmid. These nif regulatory mutations also suppressed the Nif- phenotype of Gln- strains. Thus, regulation by fixed nitrogen (possible via glutamine synthetase) occurs on the nifLA operon but not on the other six nif operons.

摘要

来自在nifL中有极性插入的菌株的四个Nif⁺回复突变体对固氮酶合成的铵和氨基酸阻遏不敏感。这些菌株在nifL区域内或附近发生了突变。去阻遏表型在含有nif⁺质粒的部分二倍体中占主导。这些nif调控突变也抑制了Gln⁻菌株的Nif⁻表型。因此，固定氮（可能通过谷氨酰胺合成酶）的调控发生在nifLA操纵子上，而不是其他六个nif操纵子上。