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Infect Immun. 1980 Nov;30(2):321-4. doi: 10.1128/iai.30.2.321-324.1980.
2
A study on experimental keratoconjunctivitis shigellosa.
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3
Immunity to keratoconjunctivitis shigellosa in rabbits after oral immunization with Shigella sonnei free endotoxin.
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10
Outer membrane proteins of Brucella abortus: isolation and characterization.流产布鲁氏菌外膜蛋白：分离与鉴定
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Acquired natural immunity following recovery from keratoconjunctivitis shigellosa.志贺氏菌性角结膜炎康复后获得的天然免疫力。
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A study of some questions of pathogenicity and immunity in dysentery using experimental models of Shigella keratoconjunctivitis in guinea pigs.利用豚鼠志贺氏菌性角膜炎实验模型对痢疾致病性和免疫性若干问题的研究。
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Experimental keratoconjunctivitis shigellosa.实验性志贺菌性角膜结膜炎
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Studies on vaccination against bacillary dysentery. 4. Oral immunization with live monotypic and combined vaccines.细菌性痢疾疫苗接种研究。4. 用活单型及联合疫苗进行口服免疫
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Studies on vaccination against bacillary dysentery. 6. Protection of children by oral immunization with streptomycin-dependent Shigella strains.细菌性痢疾疫苗接种研究。6. 用链霉素依赖型志贺氏菌株口服免疫对儿童的保护作用。
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用志贺氏菌属外膜蛋白免疫诱导的对志贺氏菌性角膜结膜炎的防护作用

Protection against keratoconjunctivitis shigellosa induced by immunization with outer membrane proteins of Shigella spp.

作者信息

Adamus G, Mulczyk M, Witkowska D, Romanowska E

出版信息

Infect Immun. 1980 Nov;30(2):321-4. doi: 10.1128/iai.30.2.321-324.1980.

DOI:10.1128/iai.30.2.321-324.1980
PMID:7002794
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC551312/
Abstract

Active immunization of guinea pigs and rabbits with outer membrane proteins (OMP) isolated from Shigella flexneri 3a and Shigella sonnei phase I protected the animals against keratoconjunctivitis shigellosa induced with the homologous or heterologous strain. Protection was also achieved in rabbits after passive immunization with anti-OMP immune serum. Active immunization with lipopolysaccharide of S. flexneri 3a did not protect rabbits against keratoconjunctivitis shigellosa.

摘要

用从福氏志贺菌3a和宋内志贺菌I相分离的外膜蛋白（OMP）对豚鼠和兔子进行主动免疫，可保护动物免受同源或异源菌株诱导的志贺菌性角膜结膜炎。用抗OMP免疫血清对兔子进行被动免疫后也能实现保护。用福氏志贺菌3a的脂多糖进行主动免疫不能保护兔子免受志贺菌性角膜结膜炎。