Camussi G, Cappio F C, Messina M, Coppo R, Stratta P, Vercellone A
Clin Nephrol. 1980 Dec;14(6):280-7.
Twenty-nine patients with Systemic Lupus Erythematosus (SLE) and 6 patients with Acute Poststreptococcal Glomerulonephritis (APGN) have been studied with the polymorphonuclear neutrophil (PMN) immunohistological technique to detect in vivo interaction between circulating immune complexes (IC) and PMN membrane receptors. Patients have been studied both at diagnosis and during follow-up and the results compared to those yielded by the C1qSP test. Our data provide evidence that the PMN immunohistological technique may prove a useful tool in monitoring IC disease. Moreover, elution studies may allow the detection and characterization of the antigens in the PMN-bound IC.
采用多形核中性粒细胞（PMN）免疫组织学技术对29例系统性红斑狼疮（SLE）患者和6例急性链球菌感染后肾小球肾炎（APGN）患者进行了研究，以检测循环免疫复合物（IC）与PMN膜受体之间的体内相互作用。对患者在诊断时和随访期间均进行了研究，并将结果与C1qSP试验的结果进行了比较。我们的数据表明，PMN免疫组织学技术可能是监测IC疾病的一种有用工具。此外，洗脱研究可能有助于检测和鉴定与PMN结合的IC中的抗原。
