Burt A D, Anthony R S, Hislop W S, Bouchier I A, MacSween R N
Gut. 1982 Mar;23(3):221-5. doi: 10.1136/gut.23.3.221.
Using an indirect immunofluorescence technique liver membrane antibodies of IgG and IgA class have been demonstrated in a statistically significant proportion of sera from patients with alcoholic hepatitis and alcoholic cirrhosis. IgG and IgA class antibodies were found respectively in 23 and 25% of 48 patients with alcoholic hepatitis, in 27 and 33% of 84 with active cirrhosis, and 67 and 58% of 12 with inactive cirrhosis. These results provide evidence of a humoral immune response in alcoholic liver disease which is directed against, as yet undefined, liver-cell membrane antigens.
运用间接免疫荧光技术，在酒精性肝炎和酒精性肝硬化患者的血清中，已证实有统计学显著比例的IgG和IgA类肝细胞膜抗体。在48例酒精性肝炎患者中，分别有23%和25%发现了IgG和IgA类抗体；在84例活动性肝硬化患者中，分别为27%和33%；在12例非活动性肝硬化患者中，分别为67%和58%。这些结果为酒精性肝病中针对尚未明确的肝细胞表面抗原的体液免疫反应提供了证据。
