Bruckner D A, Hindler J A, Martin W J, Palmer R
Antimicrob Agents Chemother. 1982 Jan;21(1):107-9. doi: 10.1128/AAC.21.1.107.
A new immunofluorescent method (FIAX) was compared with a radioimmunoassay procedure for the determination of tobramycin serum concentrations. When assaying three tobramycin control sera repeatedly, within-run and run-to-run variations by the FIAX method were all within acceptable limits, and no statistically significant differences were found. Results of 155 sera from patients who had been treated with tobramycin showed a correlation coefficient of 0.93 between the two methods. The FIAX method represents another practical alternative for determining tobramycin serum levels.
一种新的免疫荧光法（FIAX）与放射免疫分析法用于测定妥布霉素血清浓度，并进行了比较。在对三份妥布霉素对照血清进行重复测定时，FIAX法的批内和批间变异均在可接受范围内，且未发现统计学上的显著差异。对155例接受妥布霉素治疗患者的血清检测结果显示，两种方法之间的相关系数为0.93。FIAX法是测定妥布霉素血清水平的另一种实用方法。
