Hruska J F, Morrow P E, Suffin S C, Douglas R G
Antimicrob Agents Chemother. 1982 Jan;21(1):125-30. doi: 10.1128/AAC.21.1.125.
Ribavirin reduced the amount of respiratory syncytial virus in nasal turbinates and lung tissues of experimentally infected cotton rats by over 90%. An effect was seen when the drug was given either intraperitoneally or by aerosol; however, the antiviral effect was achieved at much lower doses when delivered by the aerosol route. No animal deaths due to the drug were seen.
利巴韦林使实验感染的棉鼠鼻甲和肺组织中的呼吸道合胞病毒数量减少了90%以上。无论是腹腔注射还是雾化给药，均可见此效果；然而，通过雾化途径给药时，在低得多的剂量下即可达到抗病毒效果。未见因该药物导致动物死亡的情况。
