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Radioimmunoassay of pregnanediol concentrations in early morning urine specimens for assessment of luteal function in women.

作者信息

Chatterton R T, Haan J N, Jenco J M, Cheesman K L

出版信息

Fertil Steril. 1982 Mar;37(3):361-6.

PMID:7060787
Abstract

A radioimmunoassay has been developed that employs a readily available radioligand 3H-20alpha-hydroxy-4-pregnen-3-one for the determination of pregnanediol glucuronide in urine. The unextracted steroid is assayed directly after dilution of urine with the use of an antiserum produced to a thyroglobulin conjugate of pregnanediol glucuronide. The assay has been validated, and the ability to assess luteal function by measurement of the concentration of pregnanediol glucuronide in early morning urine specimens has been demonstrated.

摘要

相似文献

1
Radioimmunoassay of pregnanediol concentrations in early morning urine specimens for assessment of luteal function in women.
Fertil Steril. 1982 Mar;37(3):361-6.
2
The concentrations of urinary oestrone-3-glucuronide, LH and pregnanediol-3alpha-glucuronide as indices of ovarian function.尿雌酮-3-葡萄糖醛酸苷、促黄体生成素和孕二醇-3α-葡萄糖醛酸苷的浓度作为卵巢功能指标。
Acta Endocrinol (Copenh). 1979 Feb;90(2):336-48. doi: 10.1530/acta.0.0900336.
3
The measurement of steroid glucuronides in urine from mice to monitor gonadal function. I. Pregnanediol-3 alpha-glucuronide as an index of progestogen output.通过测量小鼠尿液中的类固醇葡萄糖醛酸苷来监测性腺功能。I. 孕二醇-3α-葡萄糖醛酸苷作为孕激素分泌指标。
Endocrinology. 1978 Dec;103(6):2342-8. doi: 10.1210/endo-103-6-2342.
4
Characterization of luteal function by measuring the cumulative concentration of serum progesterone and urine pregnanediol-3 alpha-monoglucuronide.通过测量血清孕酮和尿孕二醇-3α-单葡萄糖醛酸苷的累积浓度来表征黄体功能。
J Endocrinol Invest. 1983 Jun;6(3):169-72. doi: 10.1007/BF03350602.
5
Determination of ovarian function using first morning urine steroid assays.使用晨尿类固醇检测法测定卵巢功能。
Obstet Gynecol. 1981 Jul;58(1):5-9.
6
The effect of conception on the concentration of urinary oestrone-3-glucuronide, LH/hCG and pregnanediol-3 alpha-glucuronide.
Acta Endocrinol (Copenh). 1980 Feb;93(2):228-33. doi: 10.1530/acta.0.0930228.
7
Serum progesterone in nonpregnant women. I. Comparative study of serum progesterone concentration and urinary pregnanediol excretion.非孕期女性的血清孕酮。I. 血清孕酮浓度与尿孕二醇排泄量的对比研究。
Am J Obstet Gynecol. 1974 Apr 15;118(8):1054-63.
8
Relationship of luteinizing hormone, pregnanediol-3-glucuronide, and estriol-16-glucuronide in urine of infertile women with endometriosis.患有子宫内膜异位症的不孕女性尿液中促黄体生成素、孕二醇-3-葡萄糖醛酸苷和雌三醇-16-葡萄糖醛酸苷的关系。
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9
Measurement of glucuronometabolites of 17 beta-estradiol and progesterone in diluted overnight urine. An approach to the study of luteal insufficiency.稀释过夜尿中17β-雌二醇和孕酮葡萄糖醛酸代谢物的测定。黄体功能不全的一种研究方法。
J Steroid Biochem. 1987;27(1-3):399-404. doi: 10.1016/0022-4731(87)90333-5.
10
Application of penicillinase linked ELISA of pregnanediol glucuronide for detection of ovulation and assessment of corpus luteal function.青霉素酶联免疫吸附测定孕二醇葡萄糖醛酸苷在排卵检测及黄体功能评估中的应用。
Endocrinol Jpn. 1987 Aug;34(4):465-72. doi: 10.1507/endocrj1954.34.465.

引用本文的文献

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The Use of Estrone-3-Glucuronide and Pregnanediol-3-Glucuronide Excretion Rates to Navigate the Continuum of Ovarian Activity.利用雌酮-3-葡萄糖醛酸苷和孕二醇-3-葡萄糖醛酸苷排泄率来把握卵巢活动的连续过程。
Front Public Health. 2018 May 31;6:153. doi: 10.3389/fpubh.2018.00153. eCollection 2018.
2
The use of biochemical assays in epidemiologic studies of reproduction.生化检测在生殖流行病学研究中的应用。
Environ Health Perspect. 1987 Nov;75:29-35. doi: 10.1289/ehp.877529.