Stockwell P A
Nucleic Acids Res. 1982 Jan 11;10(1):115-25. doi: 10.1093/nar/10.1.115.
The program described allows for the creation and manipulation of files of DNA sequence data up to very great lengths. The program uses its own paging system to load segments of the sequence into a small internal buffer so that the program does not have excessive memory requirements. The program offers a menu of functions to the user, and has been written to be forgiving of user errors. A code for the generalised specification of bases as a series of groups (i.e. A or T, Purine, etc.) has been devised and can be used in search specifications or in sequence files. Versions of the program have been developed to run with special efficiency under DIGITAL's RT11 operating system or to run under systems with a suitable implementation of FORTRAN VI.
所描述的程序能够创建和处理长度极大的DNA序列数据文件。该程序使用自身的分页系统将序列片段加载到一个小型内部缓冲区中,从而使程序无需过多内存。该程序为用户提供了一个功能菜单,并且编写得能够容忍用户错误。已经设计出一种将碱基作为一系列组(即A或T、嘌呤等)进行通用指定的代码,可用于搜索规范或序列文件中。该程序的多个版本已经开发出来,以便在数字公司的RT11操作系统下高效运行,或者在具有适用于FORTRAN VI实现的系统下运行。