大肠癌患者的呼出气甲烷
Breath-methane in patients with cancer of the large bowel.
作者信息
Haines A, Metz G, Dilawari J, Blendis L, Wiggins H
出版信息
Lancet. 1977 Sep 3;2(8036):481-3. doi: 10.1016/s0140-6736(77)91605-1.
In 30 patients with cancer of the large bowel, 24 (80%) had detectable levels of methane in their breath, compared with 25 (39%) of 64 patients with non-malignant large-bowel disease and 83 (40%) of 208 subjects without large-bowel disease. These findings suggest that there may be a difference in anaerobic intestinal flora between patients with cancer of the large bowel and those without the disease. This difference may antedate the development of the tumour or, alternatively, result from the tumour.
在30例大肠癌患者中，24例（80%）呼出气体中可检测到甲烷，相比之下，64例非恶性大肠疾病患者中有25例（39%）可检测到甲烷，208例无大肠疾病的受试者中有83例（40%）可检测到甲烷。这些发现表明，大肠癌患者与无该病患者的肠道厌氧菌群可能存在差异。这种差异可能在肿瘤发生之前就已存在，或者是由肿瘤导致的。
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