滑液乳酸测定在化脓性关节炎诊断与治疗中的应用
Synovial fluid lactic acid measurement in the diagnosis and management of septic arthritis.
作者信息
Riordan T, Doyle D, Tabaqchali S
出版信息
J Clin Pathol. 1982 Apr;35(4):390-4. doi: 10.1136/jcp.35.4.390.
Abstract
An improved method of lactic acid estimation by gas liquid chromatography (GLC) is described. Synovial fluid lactic acid estimation was performed on 52 patients (15 with septic arthritis and 37 with non-septic arthropathies) and compared to routine microbiological methods and white cell counts. Lactic acid was found to be a useful and rapid test for differentiating between septic and non-septic arthritis being markedly raised (greater than 12 mmol/l) in all the septic joints. Raised lactic acid concentrations were of particular diagnostic value in patients in whom antibiotic therapy had commenced before joint aspiration. The results of lactic acid estimation on sequential samples were helpful in assessing the response of septic arthritis to treatment.
摘要
本文描述了一种通过气液色谱法（GLC）改进的乳酸测定方法。对52例患者（15例为化脓性关节炎，37例为非化脓性关节病）的滑液进行了乳酸测定，并与常规微生物学方法和白细胞计数进行了比较。发现乳酸是区分化脓性和非化脓性关节炎的一种有用且快速的检测方法，在所有化脓性关节中乳酸水平均显著升高（大于12 mmol/l）。在关节穿刺前已开始抗生素治疗的患者中，乳酸浓度升高具有特别的诊断价值。对连续样本进行乳酸测定的结果有助于评估化脓性关节炎的治疗反应。
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