Daikoku N H, Kaltreider D F, Khouzami V A, Spence M, Johnson J W
Obstet Gynecol. 1982 Jan;59(1):13-20.
Preterm and term deliveries were analyzed at The Johns Hopkins Hospital from January 1, 1976, through December 31, 1977, to determine maternal infection risks associated with premature rupture of the membranes (PROM). Gravidas who delivered preterm infants demonstrated an increased incidence of endometritis with or without PROM. The risk of endometritis attributable solely to PROM was insignificant compared with the risk attributable to preterm delivery. These findings implicate infection in the mechanism of preterm labor, with or without PROM.
1976年1月1日至1977年12月31日期间，约翰霍普金斯医院对早产和足月分娩情况进行了分析，以确定与胎膜早破（PROM）相关的母体感染风险。分娩早产儿的孕妇，无论有无胎膜早破，子宫内膜炎的发病率均有所增加。与早产导致的风险相比，仅由胎膜早破导致的子宫内膜炎风险微不足道。这些发现表明，无论有无胎膜早破，感染都参与了早产的机制。
