Kay B A, Wachsmuth K, Gemski P
J Clin Microbiol. 1982 Jun;15(6):1161-3. doi: 10.1128/jcm.15.6.1161-1163.1982.
In a study of 103 strains of Yersinia enterocolitica, 10 strains were found to be lethal for mice and to possess 42- and 82-megadalton plasmids. This association was statistically significant (P much less than 0.001). Serotypes of Y. enterocolitica previously considered avirulent were found to possess these plasmids and to be lethal for mice. A spontaneous derivative of one strain contained only the 82-megadalton plasmid and was lethal for mice anyway. This virulence-associated plasmid is a potential diagnostic tool for the clinical or public health laboratory which must delineate pathogenic strains of Y. enterocolitica.
在一项对103株小肠结肠炎耶尔森氏菌的研究中，发现有10株对小鼠具有致死性，并带有42兆道尔顿和82兆道尔顿的质粒。这种关联具有统计学显著性（P远小于0.001）。以前认为无毒力的小肠结肠炎耶尔森氏菌血清型被发现带有这些质粒并对小鼠具有致死性。一株菌的自发衍生物只含有82兆道尔顿的质粒，但无论如何对小鼠仍具有致死性。这种与毒力相关的质粒对于必须鉴别小肠结肠炎耶尔森氏菌致病菌株的临床或公共卫生实验室来说是一种潜在的诊断工具。
