Metabolism of 5-methyltetrahydrofolate by rats bearing the Walker 256 carcinosarcoma.
作者信息
Kennelly J C, Blair J A, Pheasant A E
出版信息
Br J Cancer. 1982 Sep;46(3):440-3. doi: 10.1038/bjc.1982.222.
Abstract
摘要
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Metabolism of 5-methyltetrahydrofolate by rats bearing the Walker 256 carcinosarcoma.携带Walker 256癌肉瘤大鼠对5-甲基四氢叶酸的代谢
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[Tumor growth and liver regeneration. Studies of Walker carcinosarcoma 256 in the rat].
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Folate polyglutamate biosynthesis in the liver, tumour and intestine of rats bearing the Walker 256 carcosarcinoma.携带Walker 256癌肉瘤的大鼠肝脏、肿瘤及肠道中叶酸多聚谷氨酸的生物合成
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Regeneration of tetrahydrohomofolate in cells. Possible basis for antitumor activity of homofolates.细胞中四氢高叶酸的再生。高叶酸抗肿瘤活性的可能基础。
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Failure of systemic ketosis to control cachexia and the growth rate of the Walker 256 carcinosarcoma in rats.全身性酮症未能控制大鼠Walker 256癌肉瘤的恶病质及生长速率。
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L-methionase: a therapeutic enzyme to treat malignancies.L-甲硫氨酸酶：一种用于治疗恶性肿瘤的治疗性酶。
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本文引用的文献
1
Folate catabolism in tumour-bearing rats and rats treated with methotrexate.荷瘤大鼠及甲氨蝶呤治疗大鼠体内的叶酸分解代谢
Br J Cancer. 1981 Nov;44(5):700-8. doi: 10.1038/bjc.1981.256.
2
Vitamin B 12 dependent methionine biosynthesis in cultured mammalian cells.培养的哺乳动物细胞中维生素B12依赖的甲硫氨酸生物合成
Biochemistry. 1969 Sep;8(9):3496-9. doi: 10.1021/bi00837a002.
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The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture.同型胱氨酸替代甲硫氨酸对培养的成年哺乳动物恶性及正常细胞存活的影响。
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1133-6. doi: 10.1073/pnas.71.4.1133.
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N5-methyltetrahydrofolate: homocysteine methyltransferase activity in extracts from normal, malignant and embryonic tissue culture cells.
Biochem Biophys Res Commun. 1974 Mar 25;57(2):417-25. doi: 10.1016/0006-291x(74)90947-4.
5
Retained folates in the rat.大鼠体内留存的叶酸。
Biochem J. 1977 Jun 15;164(3):601-5. doi: 10.1042/bj1640601.
6
The metabolic fate of (2-14C)folic acid and a mixture of (2-14C)- and (3',5',9-3h)-folic acid in the rat.（2-¹⁴C）叶酸以及（2-¹⁴C）-和（3′,5′,9-³H）-叶酸混合物在大鼠体内的代谢归宿
Biochem J. 1978 Aug 15;174(2):579-83. doi: 10.1042/bj1740579.
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Dihydrofolate reductase: the current story.
Nature. 1979 Dec 13;282(5740):674-5. doi: 10.1038/282674a0.
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The metabolism of 5-methyltetrahydrofolic acid in the rat [proceedings].大鼠体内5-甲基四氢叶酸的代谢[会议论文集]
Biochem Soc Trans. 1979 Aug;7(4):648-9. doi: 10.1042/bst0070648.
10
The identification of p-acetamidobenzoate as a folate degradation product in rat urine.对大鼠尿液中对乙酰氨基苯甲酸盐作为叶酸降解产物的鉴定。
Biochem J. 1979 Mar 15;178(3):795-797. doi: 10.1042/bj1780795.
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