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细胞色素b - 245参与人类中性粒细胞的呼吸爆发。

Involvement of cytochrome b-245 in the respiratory burst of human neutrophils.

作者信息

Borregaard N, Simons E R, Clark R A

出版信息

Infect Immun. 1982 Dec;38(3):1301-3. doi: 10.1128/iai.38.3.1301-1303.1982.

DOI:10.1128/iai.38.3.1301-1303.1982
PMID:7152673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC347891/
Abstract

The cytochrome b 245 of human neutrophils was reduced when the neutrophils under anaerobic conditions were stimulated by serum-treated zymosan, immune complexes, or phorbol myristate acetate. Reintroduction of oxygen rapidly reoxidized the cytochrome; azide was without effect on any of these reactions. This indicates that cytochrome b 245 participates in the respiratory burst of neutrophils.

摘要

当在厌氧条件下的嗜中性粒细胞受到血清处理的酵母聚糖、免疫复合物或佛波醇肉豆蔻酸酯刺激时,人嗜中性粒细胞的细胞色素b 245会被还原。重新引入氧气会迅速使细胞色素再氧化;叠氮化物对任何这些反应均无影响。这表明细胞色素b 245参与嗜中性粒细胞的呼吸爆发。

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Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.人类中性粒细胞杀菌氧化酶的β-细胞色素成分的亚细胞定位:激活过程中的易位
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4
Subcellular localization and dynamics of components of the respiratory burst oxidase.呼吸爆发氧化酶组分的亚细胞定位与动态变化
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本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes.吞噬作用的生化基础。I. 多形核白细胞吞噬颗粒过程中的代谢变化。
J Biol Chem. 1959 Jun;234(6):1355-62.
3
Absence of cytochrome b reduction in stimulated neutrophils from both female and male patients with chronic granulomatous disease.患有慢性肉芽肿病的女性和男性患者的受刺激中性粒细胞中细胞色素b还原缺失。
FEBS Lett. 1980 Jan 28;110(1):111-4. doi: 10.1016/0014-5793(80)80035-4.
4
Cytochrome b-245 of neutrophils is also present in human monocytes, macrophages and eosinophils.中性粒细胞的细胞色素b - 245也存在于人类单核细胞、巨噬细胞和嗜酸性粒细胞中。
Biochem J. 1981 Apr 15;196(1):363-7. doi: 10.1042/bj1960363.
5
Energy metabolism of human neutrophils during phagocytosis.吞噬作用期间人类中性粒细胞的能量代谢
J Clin Invest. 1982 Sep;70(3):550-7. doi: 10.1172/jci110647.
6
Activation of the glycogenolytic cascade in human polymorphonuclear leucocytes by different phagocytic stimuli.
Eur J Clin Invest. 1981 Aug;11(4):257-63. doi: 10.1111/j.1365-2362.1981.tb02114.x.
7
Role of oxygen in antibody-dependent cytotoxicity mediated by monocytes and neutrophils.氧气在单核细胞和中性粒细胞介导的抗体依赖性细胞毒性中的作用。
J Clin Invest. 1980 Oct;66(4):676-83. doi: 10.1172/JCI109904.
8
Studies of the metabolic activity of leukocytes from patients with a genetic abnormality of phagocytic function.对具有吞噬功能遗传异常患者的白细胞代谢活性的研究。
J Clin Invest. 1967 Sep;46(9):1422-32. doi: 10.1172/JCI105634.
9
Iodination of bacteria: a bactericidal mechanism.细菌的碘化作用:一种杀菌机制。
J Exp Med. 1967 Dec 1;126(6):1063-78. doi: 10.1084/jem.126.6.1063.
10
Quantitative phagocytosis by neutrophils. I. A new method with immune complexes.
J Immunol. 1973 Dec;111(6):1771-6.