Maurer R G, Damasio A R
J Autism Dev Disord. 1982 Jun;12(2):195-205. doi: 10.1007/BF01531309.
Analysis of the abnormalities present in autistic patients, using standard methods of clinical inference, leads to the conclusion that the manifestations of childhood autism correlate best with the manifestations of dysfunction in the frontal tier of the ring of phylogenetically older cortex located on the mesial surface of the frontal and temporal lobes ("mesocortex" or "mesolimbic cortex") and with the manifestations of dysfunction in the striatum. These structures are distinctive in ways that suggest possible etiologies. The observations and inferences that lead to these conclusions are outlined and are supplemented by data from recent studies by the authors. Emphasis is placed on disorders of motility, communication, and attention and perception.
运用临床推理的标准方法对自闭症患者存在的异常情况进行分析，得出的结论是，儿童自闭症的表现与位于额叶和颞叶内侧表面的进化上较古老的皮质环的额叶层（“中间皮质”或“边缘叶皮质”）功能障碍的表现以及纹状体功能障碍的表现最为相关。这些结构具有独特之处，提示了可能的病因。本文概述了得出这些结论的观察和推理，并补充了作者近期研究的数据。重点放在运动、交流以及注意力和感知方面的障碍。
