Williams A J, Osman J, Skinner C
Thorax. 1982 Aug;37(8):617-9. doi: 10.1136/thx.37.8.617.
Naftidrofuryl enhances oxidative phosphorylation and might therefore be expected to improve exercise tolerance and breathlessness in advanced chronic bronchitis. This hypothesis was tested in a four-week placebo-controlled trial in 11 bronchitic patients. Seven patients completed the study. There was no evidence of any benefit from naftidrofuryl either subjectively or after a 12-minute walking test.
萘呋胺酯可增强氧化磷酸化作用，因此可能有望改善晚期慢性支气管炎患者的运动耐量和呼吸急促症状。在一项针对11名支气管炎患者进行的为期四周的安慰剂对照试验中，对这一假设进行了验证。7名患者完成了该研究。无论是主观上还是在12分钟步行测试后，均未发现萘呋胺酯有任何益处的证据。
