Kass M A, Palmberg P, Becker B, Miller J P
Arch Ophthalmol. 1978 Dec;96(12):2207-8. doi: 10.1001/archopht.1978.03910060509006.
Histocompatibility (HLA) antigen typing was performed on 306 patients who had been studied and classified carefully. Black individuals with primary open-angle glaucoma (POAG) had no significant differences in HLA antigen prevalences from black control subjects. In one white population with POAG, a significant decrease in HLA-A1, a significant increase in HLA-Aw31, and a significant increase in the antigen combination HLA-B7 and HLA-Bw22 were noted. However, these differences were not confirmed in a second white population with POAG. We concluded that associations between the A and B loci of the HLA antigen system and POAG were not as impressive as has been previously reported.
对306例经过仔细研究和分类的患者进行了组织相容性（HLA）抗原分型。患有原发性开角型青光眼（POAG）的黑人个体与黑人对照受试者在HLA抗原流行率方面没有显著差异。在一个患有POAG的白人人群中，发现HLA - A1显著减少，HLA - Aw31显著增加，以及抗原组合HLA - B7和HLA - Bw22显著增加。然而，在第二个患有POAG的白人人群中未证实这些差异。我们得出结论，HLA抗原系统的A和B位点与POAG之间的关联并不像先前报道的那样显著。
