Ivanova E A
Biull Eksp Biol Med. 1981 Feb;91(2):218-9.
The time course of uptake of testosterone-1 alpha, 2 alpha-3H (n) and (4-14C)-estradiol by homologous tissue rudiments of the developing reproductive system of rabbit embryos of both sexes was studied in in-vitro experiments from the 18th till the 25th day of development. It was found that the same rudiments of the target organs of the embryos of both sexes are capable of uptaking both hormones. At the "crucial" moment of sexual differentiation (on the 21st day) the uptake of both hormones in the genital tubercle and in the urogenital sinus was greater in female embryos than in male ones. In males, the uptake of androgen was higher than that of estrogen. At the same time the uptake of testosterone-1 alpha, 2 alpha-3H(n) by the genital ducts was higher in male embryos than in female ones.
在体外实验中，研究了从发育第18天到第25天，雌雄兔胚胎发育中的生殖系统同源组织原基对睾酮-1α，2α-3H（n）和（4-14C）-雌二醇的摄取时间进程。结果发现，雌雄胚胎的靶器官相同原基都能够摄取这两种激素。在性分化的“关键”时刻（第21天），雌性胚胎的生殖结节和泌尿生殖窦中两种激素的摄取量均高于雄性胚胎。在雄性中，雄激素的摄取高于雌激素。同时，雄性胚胎生殖管道对睾酮-1α，2α-3H（n）的摄取高于雌性胚胎。
