Shapira Y, Deckelbaum R, Statter M, Tennenbaum A, Aker M, Yarom R
Arch Dis Child. 1981 Apr;56(4):287-91. doi: 10.1136/adc.56.4.287.
Three children with Reye's syndrome are described. One child died, the second had mild and transient illness, and the third had recurrent episodes. In all 3 children a muscle biopsy showed pronounced infiltration of the myofibres with fat microdroplets as shown by the oil red O stain and by electron microscopical examination. We suggest that needle biopsy of muscle may be a quick and safe aid to the diagnosis of Reye's syndrome, and may be preferable to liver biopsy in view of the pronounced tendency to bleed in Reye's syndrome.
本文描述了3例患有瑞氏综合征的儿童。1例儿童死亡，第2例病情轻微且为一过性，第3例有反复发作。所有3例儿童的肌肉活检均显示，油红O染色及电子显微镜检查表明肌纤维有明显的脂肪微滴浸润。我们认为，肌肉穿刺活检可能是一种快速且安全的辅助诊断瑞氏综合征的方法，鉴于瑞氏综合征有明显的出血倾向，肌肉穿刺活检可能比肝脏活检更可取。
