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成人沙眼衣原体感染的临床表现与发病率。

The presentation and incidence of paratrachoma in adults.

作者信息

Tullo A B, Richmond S J, Easty D L

出版信息

J Hyg (Lond). 1981 Aug;87(1):63-9. doi: 10.1017/s0022172400069242.

Abstract

Thirteen definite and 3 probable cases of chlamydial eye infection were diagnosed in young adults attending the Bristol Eye Hospital between June 1978 and May 1980, and incidence of about 1 case per 44000 per year in the 15 to 44-year-old community served by this hospital, and 1 per 100000 in the total population of this community. These patients presented with a sub-acute follicular conjunctivitis or kerato-conjunctivitis, which had usually been present for several weeks and had often failed to respond to topical chloramphenicol treatment before presentation. Sera obtained from 14 patients, all had chlamydial antibody titres of 64 or more. Over the same period of time, an estimated 2500 patients per year from the same community attended the Venereology Department at the Bristol Royal Infirmary with genital chlamydial infections. These figures suggest that chlamydial infection of the eye complicates no more than 1 in 300 chlamydial infections of the genital tract in adults.

摘要

1978年6月至1980年5月期间,在布里斯托尔眼科医院就诊的年轻人中诊断出13例确诊的衣原体眼部感染病例和3例可能的病例,在该医院服务的15至44岁社区中,每年发病率约为每44000人中有1例,在该社区总人口中为每100000人中有1例。这些患者表现为亚急性滤泡性结膜炎或角膜结膜炎,通常已持续数周,就诊前对局部氯霉素治疗往往无效。从14例患者中采集的血清,衣原体抗体滴度均为64或更高。在同一时期,估计每年有2500名来自同一社区的患者因生殖器衣原体感染前往布里斯托尔皇家医院性病科就诊。这些数据表明,在成人中,眼部衣原体感染在生殖器衣原体感染中所占比例不超过300分之一。

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