Wald N J, Idle M, Boreham J, Bailey A
J Epidemiol Community Health. 1981 Mar;35(1):23-4. doi: 10.1136/jech.35.1.23.
Cigarette consumption and inhaling, assessed using carboxyhaemoglobin levels, were studied in 1786 men to investigate the importance of tar and nicotine as determinants of smoking habits. No prior warning was given that smoking habits would be studied. Neither nicotine nor tar yields materially influenced the number of cigarettes smoked a day. Both nicotine and tar yields were negatively associated with inhaling (p less than 0.001) but after allowing for either of the two yields the effect of the other on inhaling was no longer statistically significant. There was, therefore, no indication as to whether nicotine or tar was the more important determinant of smoking habit.
通过检测碳氧血红蛋白水平来评估的香烟消费量和吸入量，在1786名男性中进行了研究，以调查焦油和尼古丁作为吸烟习惯决定因素的重要性。事先未告知将研究吸烟习惯。尼古丁和焦油含量均未对每日吸烟数量产生实质性影响。尼古丁和焦油含量均与吸入量呈负相关（p<0.001），但在考虑其中任何一种含量后，另一种含量对吸入量的影响不再具有统计学意义。因此，没有迹象表明尼古丁或焦油哪个是吸烟习惯更重要的决定因素。
