Rothman J E
Science. 1981 Sep 11;213(4513):1212-9. doi: 10.1126/science.7268428.
The Golgi apparatus consists of distinct cis and trans compartments that may act sequentially to refine the protein export of the endoplasmic reticulum by removing escaped endoplasmic reticulum proteins. Refinement may be a multistage process akin to fractional distillation; the stack of cisternae comprising the cis Golgi may be the plates in this distillation tower. The trans Golgi, consisting of the last one or two cisternae, may be the receiver that collects from the cis Golgi only its most refined fraction for later distribution to specific locations throughout the cell.
高尔基体由不同的顺面和反面区室组成，这些区室可能通过去除逃逸的内质网蛋白，依次作用以优化内质网的蛋白质输出。优化可能是一个类似于分馏的多阶段过程；构成顺面高尔基体的扁平囊堆叠可能是这个蒸馏塔中的塔板。反面高尔基体由最后一两个扁平囊组成，可能是接收器，它仅从顺面高尔基体收集其最精制的部分，以便随后分发到细胞内的特定位置。
