Finkelstein F O, Forman B H, Marieb N J, Neely J, Santacroce S
Yale J Biol Med. 1981 Mar-Apr;54(2):95-100.
The present study describes our experience with CAPD in an unselected group of patients presenting with endstage renal failure. Twenty-three consecutive patients were offered CAPD, in-center, and home hemodialysis. Twenty-two patients selected CAPD, including 14 patients more than 60 years of age, four patients with diabetes, and one with multiple myeloma. CAPD training was performed in an out-of-hospital office facility. One patient returned to hemodialysis following the development of resistant Pseudomonas peritonitis, two patients died of a myocardial infarction, and one patient died with a GI bleed. The other 18 patients are doing well. Assessment of 17 patients maintained on therapy for four months or more revealed that the patients are less depressed, less organic, and have fewer physical symptoms than previously reported for a comparable group of patients maintained on hemodialysis for a similar period of time. In conclusion, CAPD can be successfully employed, at least for the initial months of therapy, to treat the vast majority of patients with endstage renal disease. CAPD training and follow-up care can be provided in an out-of-hospital office facility.
本研究描述了我们在一组未经挑选的终末期肾衰竭患者中应用持续性非卧床腹膜透析(CAPD)的经验。连续23例患者被提供了CAPD、中心血液透析和家庭血液透析。22例患者选择了CAPD,其中包括14例年龄超过60岁的患者、4例糖尿病患者和1例多发性骨髓瘤患者。CAPD培训在院外办公场所进行。1例患者因发生耐药性铜绿假单胞菌腹膜炎后转回血液透析,2例患者死于心肌梗死,1例患者死于胃肠道出血。其他18例患者情况良好。对17例接受治疗4个月或更长时间的患者进行评估发现,与之前报道的在相似时间段接受血液透析的类似患者组相比,这些患者的抑郁程度更低、器质性病变更少且身体症状更少。总之,至少在治疗的最初几个月,CAPD可成功用于治疗绝大多数终末期肾病患者。CAPD培训和后续护理可在院外办公场所提供。