Hillbom M, Kaste M
J Neurol Neurosurg Psychiatry. 1981 Jun;44(6):523-6. doi: 10.1136/jnnp.44.6.523.
Seventy-five consecutive patients aged 15 to 55 years with aneurysmal subarachnoid haemorrhage verified by CSF examination and cerebral angiography or at necropsy were studied. In 19 cases (25%; four women and 15 men) the bleeding was preceded within 24 hours by a bout of alcohol drinking. Alcohol-related cases composed 33% and 14% of the patients in the age groups 15-40 and 41-55 years, respectively. Alcohol intoxication preceding the subarachnoid haemorrhage was two to four times as common in male and three to five times as common in female patients as alcohol intoxication in the general Finnish population of the same age and sex. Occasional alcohol intoxication seems to carry an increased risk of aneurysmal subarachnoid haemorrhage.
对75例年龄在15至55岁之间、经脑脊液检查和脑血管造影或尸检证实为动脉瘤性蛛网膜下腔出血的连续患者进行了研究。其中19例(25%;4名女性和15名男性)在出血前24小时内有饮酒史。酒精相关病例在15 - 40岁和41 - 55岁年龄组中分别占患者的33%和14%。蛛网膜下腔出血前的酒精中毒在男性患者中是同年龄和性别的芬兰普通人群的两到四倍,在女性患者中是三到五倍。偶尔的酒精中毒似乎会增加动脉瘤性蛛网膜下腔出血的风险。