肝酶浓度作为慢性无症状乙肝携带者潜在传染性的衡量指标。
Liver enzyme concentrations as measure of possible infectivity in chronic asymptomatic carriers of hepatitis B.
作者信息
Barbara J A, Mijovic V, Cleghorn T E, Tedder R S, Briggs M
出版信息
Br Med J. 1978 Dec 9;2(6152):1600-2. doi: 10.1136/bmj.2.6152.1600.
Fifty-two British-born blood donors who were chronic carriers of hepatitis B surface antigen (HBsAg) were tested for the presence of hepatitis B e antigen (HBeAg) and antibody to HBeAg by an immunoradiometric assay. The presence of HBeAg was closely associated with a slight rise in serum liver enzyme concentrations, a high HBsAg titre, and male sex. We suggest that the finding of persistently raised serum liver enzyme concentrations in an asymptomatic HBsAg carrier might be useful as a likely indicator of HBeAg and high infectivity.
对52名出生于英国的慢性乙型肝炎表面抗原（HBsAg）携带者献血者进行免疫放射分析，检测其乙型肝炎e抗原（HBeAg）及抗-HBeAg抗体的存在情况。HBeAg的存在与血清肝酶浓度略有升高、HBsAg高滴度以及男性性别密切相关。我们认为，在无症状HBsAg携带者中发现血清肝酶浓度持续升高，可能有助于作为HBeAg及高传染性的一个潜在指标。
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