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Z-DNA 内反应位点的静电势和空间可及性。

The electrostatic potential and steric accessibility of reactive sites within Z-DNA.

作者信息

Zakrzewska K, Lavery R, Pullman A, Pullman B

出版信息

Nucleic Acids Res. 1980 Sep 11;8(17):3917-32. doi: 10.1093/nar/8.17.3917.

DOI:10.1093/nar/8.17.3917
PMID:7443517
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC324204/
Abstract

A theoretical study of indices potentially useful for investigation of the reactivity of the recently discovered Z-DNA double helix is presented. The electrostatic potential minima and the steric accessibility of reactive sites are calculated. The effect of screening the phosphate groups by metal cations is investigated. The results are compared with those for the B-DNA double helix.

摘要

本文对可能有助于研究最近发现的Z-DNA双螺旋反应活性的指标进行了理论研究。计算了静电势极小值和反应位点的空间可及性。研究了金属阳离子对磷酸基团的屏蔽作用。并将结果与B-DNA双螺旋的结果进行了比较。

相似文献

1
The electrostatic potential and steric accessibility of reactive sites within Z-DNA.Z-DNA 内反应位点的静电势和空间可及性。
Nucleic Acids Res. 1980 Sep 11;8(17):3917-32. doi: 10.1093/nar/8.17.3917.
2
Reactivity of B and Z-DNA towards N-acetoxy-2-acetylaminofluorene.B型和Z型DNA对N-乙酰氧基-2-乙酰氨基芴的反应活性。
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Two aspects of DNA polymorphism and microheterogeneity: molecular electrostatic potential and steric accessibility.DNA多态性和微异质性的两个方面:分子静电势和空间可及性。
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The molecular electrostatic potential and steric accessibility of poly (dA-dT). poly (dA-dT) in various conformations: B-DNA, D-DNA and 'alternating-B' DNA.聚(dA-dT)·聚(dA-dT)在不同构象(B-DNA、D-DNA和“交替B”DNA)下的分子静电势和空间可及性。
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The molecular electrostatic potential, steric accessibility and hydration of Dickerson's B-DNA dodecamer d(CpGpCpGpApApTpTpCpGpCpG).迪克森B型DNA十二聚体d(CpGpCpGpApApTpTpCpGpCpG)的分子静电势、空间可及性和水合作用
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引用本文的文献

1
The molecular electrostatic potential and steric accessibility of poly (dA-dT). poly (dA-dT) in various conformations: B-DNA, D-DNA and 'alternating-B' DNA.聚(dA-dT)·聚(dA-dT)在不同构象(B-DNA、D-DNA和“交替B”DNA)下的分子静电势和空间可及性。
Nucleic Acids Res. 1981 Dec 11;9(23):6539-52. doi: 10.1093/nar/9.23.6539.
2
The molecular electrostatic potential and steric accessibility of A-DNA.A-DNA的分子静电势和空间可及性
Nucleic Acids Res. 1981 Sep 25;9(18):4677-88. doi: 10.1093/nar/9.18.4677.
3
The molecular electrostatic potential, steric accessibility and hydration of Dickerson's B-DNA dodecamer d(CpGpCpGpApApTpTpCpGpCpG).迪克森B型DNA十二聚体d(CpGpCpGpApApTpTpCpGpCpG)的分子静电势、空间可及性和水合作用
Nucleic Acids Res. 1981 Aug 11;9(15):3765-77. doi: 10.1093/nar/9.15.3765.
4
Reactivity of B and Z-DNA towards N-acetoxy-2-acetylaminofluorene.B型和Z型DNA对N-乙酰氧基-2-乙酰氨基芴的反应活性。
Nucleic Acids Res. 1982 Jul 24;10(14):4423-30. doi: 10.1093/nar/10.14.4423.
5
Guanine and 7-methylguanine amino proton exchange rates as a function of buffer pK: implications for the exchange mechanism.鸟嘌呤和7-甲基鸟嘌呤的氨基质子交换速率与缓冲液pK的关系:对交换机制的启示
Nucleic Acids Res. 1986 Sep 11;14(17):7083-92.

本文引用的文献

1
Left-handed DNA helices.左手DNA螺旋
Nature. 1980 Feb 21;283(5749):743-5. doi: 10.1038/283743a0.
2
The electrostatic molecular potential of yeast tRNAPhe. (I). The potential due to the phosphate backbone.酵母苯丙氨酸转运核糖核酸的静电分子势。(I). 磷酸主链产生的势
Nucleic Acids Res. 1980 Mar 11;8(5):1061-79. doi: 10.1093/nar/8.5.1061.
3
Salt-induced co-operative conformational change of a synthetic DNA: equilibrium and kinetic studies with poly (dG-dC).盐诱导的合成DNA的协同构象变化:聚(dG-dC)的平衡和动力学研究
J Mol Biol. 1972 Jun 28;67(3):375-96. doi: 10.1016/0022-2836(72)90457-3.
4
Solvent accessibility study on tRNAPhe.苯丙氨酸转运核糖核酸(tRNAPhe)的溶剂可及性研究
Biopolymers. 1979 Sep;18(9):2233-47. doi: 10.1002/bip.1979.360180911.
5
Molecular structure of a left-handed double helical DNA fragment at atomic resolution.原子分辨率下左手双螺旋DNA片段的分子结构。
Nature. 1979 Dec 13;282(5740):680-6. doi: 10.1038/282680a0.
6
The molecular electrostatic potential of the B-DNA helix. VI. The regions of the base pairs in poly (dG.dC) and poly (dA.dT).B型DNA螺旋的分子静电势。VI. 聚(dG.dC)和聚(dA.dT)中碱基对的区域
Nucleic Acids Res. 1979 Aug 24;6(12):3821-9. doi: 10.1093/nar/6.12.3821.