严重巴比妥类药物和对乙酰氨基酚过量：通过血液灌流同时清除两种毒物。
Severe barbiturate and paracetamol overdose: the simultaneous removal of both poisons by haemoperfusion.
作者信息
Helliwell M
出版信息
Postgrad Med J. 1980 May;56(655):363-5. doi: 10.1136/pgmj.56.655.363.
Abstract
Charcoal haemoperfusion was successful in the treatment of severe butobarbitone poisoning complicated by resistant hypotension. At the same time the rapid removal of paracetamol may have lessened the severity of the subsequent hepatic injury. The mechanism and management of shock associated with barbiturate poisoning, and the possible application of haemoperfusion in paracetamol poisoning are discussed.
摘要
血液灌流成功治疗了严重的布他比妥中毒并伴有顽固性低血压。同时，对乙酰氨基酚的快速清除可能减轻了随后肝损伤的严重程度。本文讨论了与巴比妥类中毒相关的休克机制及处理，以及血液灌流在对乙酰氨基酚中毒中的可能应用。
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本文引用的文献
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Charcoal haemoperfusion for paracetamol overdose.活性炭血液灌流治疗对乙酰氨基酚中毒。
Br J Clin Pharmacol. 1974 Jun;1(3):271-5. doi: 10.1111/j.1365-2125.1974.tb00249.x.
2
THE MECHANISM OF SHOCK FOLLOWING SUICIDAL DOSES OF BARBITURATES, NARCOTICS AND TRANQUILIZER DRUGS, WITH OBSERVATIONS ON THE EFFECTS OF TREATMENT.自杀剂量的巴比妥类药物、麻醉药和镇静剂所致休克的机制及治疗效果观察
Am J Med. 1965 Jun;38:853-63. doi: 10.1016/0002-9343(65)90004-5.
3
Shock associated with barbiturate intoxication.与巴比妥类药物中毒相关的休克。
JAMA. 1971 Jan 11;215(2):263-8.
4
Potentiation by previous drug therapy of hepatotoxicity following paracetamol overdosage.既往药物治疗对乙酰氨基酚过量后肝毒性的增强作用。
Scott Med J. 1973 Mar;18(2):56-8. doi: 10.1177/003693307301800205.
5
Plasma-paracetamol half-life and hepatic necrosis in patients with paracetamol overdosage.对乙酰氨基酚过量患者的血浆对乙酰氨基酚半衰期与肝坏死
Lancet. 1971 Mar 13;1(7698):519-22. doi: 10.1016/s0140-6736(71)91125-1.
6
Experimental drug intoxication: treatment with charcoal haemoperfusion.实验性药物中毒：用活性炭血液灌注治疗。
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7
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