活性炭血液灌流治疗对乙酰氨基酚中毒。
Charcoal haemoperfusion for paracetamol overdose.
机构信息
The Liver Unit, King's College Hospital and Medical School, Denmark Hill, London.
出版信息
Br J Clin Pharmacol. 1974 Jun;1(3):271-5. doi: 10.1111/j.1365-2125.1974.tb00249.x.
Abstract
1 A controlled trial of charcoal haemoperfusion as an early treatment for paracetamol overdose showed no benefit. 2 The plasma clearances of paracetamol by the charcoal column were variable and disappointingly small (range 4-119 ml/minute). The cumulative amounts removed were also low, mean 1.4 g (range 0.2-5.2 g). 3 No clinical problems were encountered with the technique of haemoperfusion and in particular the drop in blood platelet counts was small (mean fall 16%).
摘要
- 一项针对炭血灌流作为扑热息痛过量早期治疗的对照试验并未显示出获益。2. 炭柱对扑热息痛的血浆清除率变化不定且小得令人失望（范围 4-119 毫升/分钟）。被清除的累积量也较低，平均 1.4 克（范围 0.2-5.2 克）。3. 血液灌流技术未引发任何临床问题，特别是血小板计数下降幅度较小（平均下降 16%）。
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